Percutaneous placement of the Kimray-Greenfield vena cava filter was successfully performed in 12 consecutive patients, 10 from the right femoral vein, one from the left femoral vein, and one from the right internal jugular vein. Tract dilatation to allow placement of a 24-French sheath was easily performed and well tolerated. There was no occurrence of puncture site hematoma, significant blood loss, or postprocedural femoral vein thrombophlebitis. Percutaneous femoral vein approach is as effective as right internal jugular vein approach. The dependence on surgically obtained access for Kimray-Greenfield filter placement is no longer absolute.