-transparent.png){kind=logo}
Condensation reactions of 3-(1H-benzimidazole-2)propanoic acid (procodazol) with aromatic aldehydes were carried out resulting in lactam and acid derivatives. Basing on the spectral studies (MS, NMR) it was found that in the reaction the hydrogen atoms of the 3-methylene group of procodazol take part. 3-[2'-Acetoxyphenyl)methylene]-2,3-dihydro-1 H-pyrrole[1,2-a]benzimidazol-1-one (3c) was found to possess some analgetic properties.
Related Publications
W Kuźmierkiewicz, and
H Foks, and
E Hać, and
H Strzałkowska-Grad
January 1989,
Pakistan journal of pharmaceutical sciences,
W Kuźmierkiewicz, and
H Foks, and
E Hać, and
H Strzałkowska-Grad
February 1993,
Chemical & pharmaceutical bulletin,
W Kuźmierkiewicz, and
H Foks, and
E Hać, and
H Strzałkowska-Grad
August 2002,
Bioorganic & medicinal chemistry letters,
W Kuźmierkiewicz, and
H Foks, and
E Hać, and
H Strzałkowska-Grad
July 2022,
Molecules (Basel, Switzerland),
W Kuźmierkiewicz, and
H Foks, and
E Hać, and
H Strzałkowska-Grad
April 1990,
Archiv der Pharmazie,
W Kuźmierkiewicz, and
H Foks, and
E Hać, and
H Strzałkowska-Grad
January 2013,
Synthetic communications,
W Kuźmierkiewicz, and
H Foks, and
E Hać, and
H Strzałkowska-Grad
April 2005,
Bioorganic & medicinal chemistry,
W Kuźmierkiewicz, and
H Foks, and
E Hać, and
H Strzałkowska-Grad
July 2013,
Bioorganic & medicinal chemistry letters,
W Kuźmierkiewicz, and
H Foks, and
E Hać, and
H Strzałkowska-Grad
April 1987,
Journal of medicinal chemistry,
W Kuźmierkiewicz, and
H Foks, and
E Hać, and
H Strzałkowska-Grad
February 1992,
Chemical & pharmaceutical bulletin,
