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We have isolated and sequenced a cDNA clone coding for the human pancreatic secretory trypsin inhibitor (PSTI) from a human pancreatic cDNA library. The predicted product consists of 79 amino acids, and contains no apparent functional polypeptide other than PSTI. Southern blot analysis suggests that there is one copy of PSTI gene per haploid genome. This gene seems to be expressed not only in pancreas, but also in gastric mucosa, since a Northern blot analysis demonstrated the presence of a poly(A) RNA of the same size as in the pancreas. A comparison of sequences between human PSTI mRNA and mouse epidermal growth factor (EGF) mRNA revealed a high homology, suggesting that they share a common ancestral DNA sequence.
T Yamamoto, and
Y Nakamura, and
J Nishide, and
M Emi, and
M Ogawa, and
T Mori, and
K Matsubara
February 1995,
Nihon rinsho. Japanese journal of clinical medicine,
T Yamamoto, and
Y Nakamura, and
J Nishide, and
M Emi, and
M Ogawa, and
T Mori, and
K Matsubara
November 2004,
Nihon rinsho. Japanese journal of clinical medicine,
T Yamamoto, and
Y Nakamura, and
J Nishide, and
M Emi, and
M Ogawa, and
T Mori, and
K Matsubara
August 1999,
Nihon rinsho. Japanese journal of clinical medicine,
T Yamamoto, and
Y Nakamura, and
J Nishide, and
M Emi, and
M Ogawa, and
T Mori, and
K Matsubara
October 1990,
Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme,
T Yamamoto, and
Y Nakamura, and
J Nishide, and
M Emi, and
M Ogawa, and
T Mori, and
K Matsubara
December 1987,
Biochemical and biophysical research communications,
T Yamamoto, and
Y Nakamura, and
J Nishide, and
M Emi, and
M Ogawa, and
T Mori, and
K Matsubara
August 1985,
Gastroenterologia Japonica,
T Yamamoto, and
Y Nakamura, and
J Nishide, and
M Emi, and
M Ogawa, and
T Mori, and
K Matsubara
January 1989,
Biochemical and biophysical research communications,
T Yamamoto, and
Y Nakamura, and
J Nishide, and
M Emi, and
M Ogawa, and
T Mori, and
K Matsubara
September 1992,
Biochimica et biophysica acta,
T Yamamoto, and
Y Nakamura, and
J Nishide, and
M Emi, and
M Ogawa, and
T Mori, and
K Matsubara
December 1990,
British journal of cancer,
T Yamamoto, and
Y Nakamura, and
J Nishide, and
M Emi, and
M Ogawa, and
T Mori, and
K Matsubara
September 1985,
Kaku igaku. The Japanese journal of nuclear medicine,
