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Twenty two patients with progressive systemic sclerosis were studied by monoclonal antibodies to detect OKT4 and OKT8 positive cells. The absolute number of OKT4 and OKT8 cells was not altered as compared to control values. The ratio of T4/T8 cells slightly increased without statistical significance. The number of E-rosette forming T-cells was reduced in patients with progressive systemic sclerosis. Six months later 11 patients were reinvestigated, and similar results were obtained for the T-cell subsets and the ratio of T4/T8 positive cells. Individual data showed marked variability in the two periods of investigation without however, any correlation to the clinical findings. The sclerodermic patients had a long disease duration and showed no immunoregulatory T-cell imbalance.
L Czirják, and
P Surányi, and
K Dankó, and
G Szegedi
January 1982,
Archives of dermatological research,
L Czirják, and
P Surányi, and
K Dankó, and
G Szegedi
September 1982,
International journal of leprosy and other mycobacterial diseases : official organ of the International Leprosy Association,
L Czirják, and
P Surányi, and
K Dankó, and
G Szegedi
July 1984,
Journal of clinical pathology,
L Czirják, and
P Surányi, and
K Dankó, and
G Szegedi
April 1980,
The Journal of experimental medicine,
L Czirják, and
P Surányi, and
K Dankó, and
G Szegedi
November 1984,
International journal of radiation oncology, biology, physics,
L Czirják, and
P Surányi, and
K Dankó, and
G Szegedi
October 1982,
Clinical and experimental immunology,
L Czirják, and
P Surányi, and
K Dankó, and
G Szegedi
January 1986,
La Ricerca in clinica e in laboratorio,
L Czirják, and
P Surányi, and
K Dankó, and
G Szegedi
November 1982,
Journal of clinical & laboratory immunology,
L Czirják, and
P Surányi, and
K Dankó, and
G Szegedi
November 1982,
Klinische Wochenschrift,
L Czirják, and
P Surányi, and
K Dankó, and
G Szegedi
January 1983,
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie,
