BIOMAT Database Logo BIOMAT Database Logo

Continuous positive airway pressure by face mask in acute cardiogenic pulmonary edema. 1985

J Räsänen, and J Heikkilä, and J Downs, and P Nikki, and I Väisänen, and A Viitanen

The therapeutic efficacy of continuous positive airway pressure (CPAP) administered by face mask was studied in 40 patients with acute cardiogenic pulmonary edema and respiratory failure. Arterial blood gas values and pH, systemic arterial pressure, heart rate and respiratory rate were measured during administration of 30% oxygen with a high-flow face mask apparatus at ambient airway pressure. Twenty patients were then randomly chosen to continue ambient airway pressure breathing and 20 received 10 cm H2O of CPAP. The measurements were repeated 10, 60 and 180 minutes after therapy was initiated. During the first 10 minutes of CPAP treatment, arterial blood oxygen partial pressure increased 8 +/- 9 mm Hg (mean +/- 1 standard deviation), (p less than 0.01) and respiratory rate decreased 5 +/- 5 breaths/min (p less than 0.001). Systolic arterial pressure decreased 12 +/- 21 mm Hg (p less than 0.05), and heart rate by 10 +/- 11 beats/min (p less than 0.001). A decrease in respiratory rate by 2 +/- 5 breaths/min (p less than 0.05) was the only change that occurred in the control group. The improvement in arterial blood oxygenation persisted throughout the investigation period (p less than 0.05). Thirteen patients (65%) in the control group and 7 patients (35%) in the CPAP group met our criteria for treatment failure during the study (p = 0.068). Thus, CPAP administered by face mask improves gas exchange, decreases respiratory work, unloads circulatory stress, and may reduce the need for ventilator treatment in acute cardiogenic pulmonary edema.

UI MeSH Term Description Entries
D008297 Male Males
D008397 Masks Devices that cover the nose and mouth to maintain aseptic conditions often for the prevention of the spread of infections (e.g. COVID19) or to administer inhaled anesthetics or other gases. Mask
D008875 Middle Aged An adult aged 45 - 64 years. Middle Age
D011175 Positive-Pressure Respiration A method of mechanical ventilation in which pressure is maintained to increase the volume of gas remaining in the lungs at the end of expiration, thus reducing the shunting of blood through the lungs and improving gas exchange. Positive End-Expiratory Pressure,Positive-Pressure Ventilation,End-Expiratory Pressure, Positive,End-Expiratory Pressures, Positive,Positive End Expiratory Pressure,Positive End-Expiratory Pressures,Positive Pressure Respiration,Positive Pressure Ventilation,Positive-Pressure Respirations,Positive-Pressure Ventilations,Pressure, Positive End-Expiratory,Pressures, Positive End-Expiratory,Respiration, Positive-Pressure,Respirations, Positive-Pressure,Ventilation, Positive-Pressure,Ventilations, Positive-Pressure
D011654 Pulmonary Edema Excessive accumulation of extravascular fluid in the lung, an indication of a serious underlying disease or disorder. Pulmonary edema prevents efficient PULMONARY GAS EXCHANGE in the PULMONARY ALVEOLI, and can be life-threatening. Wet Lung,Edema, Pulmonary,Edemas, Pulmonary,Pulmonary Edemas,Lung, Wet,Lungs, Wet,Wet Lungs
D012129 Respiratory Function Tests Measurement of the various processes involved in the act of respiration: inspiration, expiration, oxygen and carbon dioxide exchange, lung volume and compliance, etc. Lung Function Tests,Pulmonary Function Tests,Function Test, Pulmonary,Function Tests, Pulmonary,Pulmonary Function Test,Test, Pulmonary Function,Tests, Pulmonary Function,Function Test, Lung,Function Test, Respiratory,Function Tests, Lung,Function Tests, Respiratory,Lung Function Test,Respiratory Function Test,Test, Lung Function,Test, Respiratory Function,Tests, Lung Function,Tests, Respiratory Function
D012131 Respiratory Insufficiency Failure to adequately provide oxygen to cells of the body and to remove excess carbon dioxide from them. (Stedman, 25th ed) Acute Hypercapnic Respiratory Failure,Acute Hypoxemic Respiratory Failure,Hypercapnic Acute Respiratory Failure,Hypercapnic Respiratory Failure,Hypoxemic Acute Respiratory Failure,Hypoxemic Respiratory Failure,Respiratory Depression,Respiratory Failure,Ventilatory Depression,Depressions, Ventilatory,Failure, Hypercapnic Respiratory,Failure, Hypoxemic Respiratory,Failure, Respiratory,Hypercapnic Respiratory Failures,Hypoxemic Respiratory Failures,Respiratory Failure, Hypercapnic,Respiratory Failure, Hypoxemic,Respiratory Failures
D005260 Female Females
D006331 Heart Diseases Pathological conditions involving the HEART including its structural and functional abnormalities. Cardiac Disorders,Heart Disorders,Cardiac Diseases,Cardiac Disease,Cardiac Disorder,Heart Disease,Heart Disorder
D006334 Heart Function Tests Examinations used to diagnose and treat heart conditions. Cardiac Function Tests,Cardiac Function Test,Function Test, Cardiac,Function Test, Heart,Function Tests, Cardiac,Function Tests, Heart,Heart Function Test,Test, Cardiac Function,Test, Heart Function,Tests, Cardiac Function,Tests, Heart Function

Related Publications

J Räsänen, and J Heikkilä, and J Downs, and P Nikki, and I Väisänen, and A Viitanen
Randomized, prospective trial of oxygen, continuous positive airway pressure, and bilevel positive airway pressure by face mask in acute cardiogenic pulmonary edema.
December 2004, Critical care medicine,
J Räsänen, and J Heikkilä, and J Downs, and P Nikki, and I Väisänen, and A Viitanen
Treatment of severe cardiogenic pulmonary edema with continuous positive airway pressure delivered by face mask.
December 1991, The New England journal of medicine,
J Räsänen, and J Heikkilä, and J Downs, and P Nikki, and I Väisänen, and A Viitanen
Does continuous positive airway pressure by face mask improve patients with acute cardiogenic pulmonary edema due to left ventricular diastolic dysfunction?
March 2005, Chest,
J Räsänen, and J Heikkilä, and J Downs, and P Nikki, and I Väisänen, and A Viitanen
Postpneumonectomy pulmonary edema treated with a continuous positive airway pressure face mask.
January 1989, Critical care medicine,
J Räsänen, and J Heikkilä, and J Downs, and P Nikki, and I Väisänen, and A Viitanen
Mortality in acute cardiogenic pulmonary edema treated with continuous positive airway pressure.
February 2009, Intensive care medicine,
J Räsänen, and J Heikkilä, and J Downs, and P Nikki, and I Väisänen, and A Viitanen
Continuous positive airway pressure (CPAP) by face mask.
September 1980, Critical care medicine,
J Räsänen, and J Heikkilä, and J Downs, and P Nikki, and I Väisänen, and A Viitanen
Noninvasive ventilation in acute cardiogenic pulmonary edema: better than continuous positive airway pressure?
January 1999, Intensive care medicine,
J Räsänen, and J Heikkilä, and J Downs, and P Nikki, and I Väisänen, and A Viitanen
Noninvasive continuous positive airway pressure in elderly cardiogenic pulmonary edema patients.
May 2004, Intensive care medicine,
J Räsänen, and J Heikkilä, and J Downs, and P Nikki, and I Väisänen, and A Viitanen
Continuous versus bilevel positive airway pressure in acute cardiogenic pulmonary edema? A good question!
December 2004, Critical care medicine,
J Räsänen, and J Heikkilä, and J Downs, and P Nikki, and I Väisänen, and A Viitanen
Continuous and bilevel positive airway pressure in the treatment of acute cardiogenic pulmonary edema.
January 2000, The American journal of emergency medicine,
Copied contents to your clipboard!