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An immunoperoxidase method using antisera specific for PG I and PG II was developed to assess PG-containing cells in the human stomach. Fundus-chief cells contained abundant PG I and less PG II. Mucus neck cells stained more frequently with anti-PG I, while antral gland cells stained only with anti-PG II. In adenocarcinoma of the corpus, isolated glands faintly staining with anti-PG I or anti-PG II were observed. In dense tumorous tissue no anti-PG I activity could be observed, while PG II sometimes remained present in residual antral glands, even in areas of heavy tumor infiltration. Focal PG II activity was also clearly demonstrated in some antral tumor cells. The immunoperoxidase technique described is suitable for further detailed studies of normal and pathological conditions of the gastric mucosa.
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H Mullink, and
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G Pals, and
J Défize, and
M Flipse, and
B D Westerveld, and
M Tas, and
J Brakké, and
J Kreuning
January 1983,
Histochemistry,
S G Meuwissen, and
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G Pals, and
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M Flipse, and
B D Westerveld, and
M Tas, and
J Brakké, and
J Kreuning
August 2005,
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S G Meuwissen, and
H Mullink, and
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March 1987,
Gastroenterology,
S G Meuwissen, and
H Mullink, and
A Bosma, and
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J Défize, and
M Flipse, and
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J Brakké, and
J Kreuning
February 1990,
European journal of cell biology,
S G Meuwissen, and
H Mullink, and
A Bosma, and
G Pals, and
J Défize, and
M Flipse, and
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M Tas, and
J Brakké, and
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July 2010,
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S G Meuwissen, and
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J Brakké, and
J Kreuning
December 1963,
The American journal of physiology,
S G Meuwissen, and
H Mullink, and
A Bosma, and
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J Kreuning
September 1980,
Gastroenterology,
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H Mullink, and
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G Pals, and
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J Kreuning
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Acta medica Indonesiana,
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J Brakké, and
J Kreuning
October 1983,
Plant physiology,
S G Meuwissen, and
H Mullink, and
A Bosma, and
G Pals, and
J Défize, and
M Flipse, and
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M Tas, and
J Brakké, and
J Kreuning
July 1990,
The Anatomical record,
