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A luteinizing hormone-releasing hormone (LH-RH)-like substance has been detected in human seminal plasma by a radioimmunoassay (RIA) with a highly specific anti-LH-RH antiserum. The seminal samples--not only the plasma itself but also the sample extracted by an acid/alcohol method--showed satisfactory displacement curves in our RIA system. The relationship between fertility and the LH-RH values in the seminal plasma was studied by comparing the peptide levels with sperm concentration and motility. By these two parameters, 103 samples were divided into four groups. In the low-concentration groups (oligozoospermic patients), the hormonal concentrations differed significantly (P less than 0.05) between those specimens demonstrating good and poor motility. These data suggest that this immunoreactive LH-RH may play a role in human spermatogenesis.
S Izumi, and
T Makino, and
R Iizuka
March 1982,
The Journal of clinical endocrinology and metabolism,
S Izumi, and
T Makino, and
R Iizuka
December 2002,
The Journal of clinical endocrinology and metabolism,
S Izumi, and
T Makino, and
R Iizuka
January 1992,
Acta veterinaria Hungarica,
S Izumi, and
T Makino, and
R Iizuka
May 1992,
South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde,
S Izumi, and
T Makino, and
R Iizuka
June 1982,
Brain research bulletin,
S Izumi, and
T Makino, and
R Iizuka
July 1980,
Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme,
S Izumi, and
T Makino, and
R Iizuka
January 1987,
The Journal of reproductive medicine,
S Izumi, and
T Makino, and
R Iizuka
January 1978,
Fertility and sterility,
S Izumi, and
T Makino, and
R Iizuka
December 1980,
Kaku igaku. The Japanese journal of nuclear medicine,
S Izumi, and
T Makino, and
R Iizuka
July 1979,
American journal of obstetrics and gynecology,
