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Various complexes of phagocytes with adsorbed (I) and entrapped (J) particles are formed during phagocytosis. Method of stereological reconstruction is proposed that allows to demonstrate the actual distribution of these complexes on the basis of morphometric analysis of their ultrathin sections. The principle of the method lies on the probability simulation of section distribution for a given distribution of complexes and on the solution of the reverse problem by stepwise determination of the relative quantity of each complex type (from the most complicated to the most simple one, when I = 0 and J = 0). The stereological analysis of phagocytosing murine peritoneal macrophages revealed an absolutely different and more adequate kinetical picture of phagocytosis, as compared to the morphometric data.
V V Shcherbukhin, and
A V Khramtsov, and
I A Morozov, and
E P Senchenkov, and
V M Zemskov
January 1981,
Advances in clinical chemistry,
V V Shcherbukhin, and
A V Khramtsov, and
I A Morozov, and
E P Senchenkov, and
V M Zemskov
October 1978,
Virchows Archiv. A, Pathological anatomy and histology,
V V Shcherbukhin, and
A V Khramtsov, and
I A Morozov, and
E P Senchenkov, and
V M Zemskov
January 1997,
European journal of histochemistry : EJH,
V V Shcherbukhin, and
A V Khramtsov, and
I A Morozov, and
E P Senchenkov, and
V M Zemskov
January 1996,
Folia morphologica,
V V Shcherbukhin, and
A V Khramtsov, and
I A Morozov, and
E P Senchenkov, and
V M Zemskov
January 1980,
Journal of electron microscopy,
V V Shcherbukhin, and
A V Khramtsov, and
I A Morozov, and
E P Senchenkov, and
V M Zemskov
January 1986,
Problemy tuberkuleza,
V V Shcherbukhin, and
A V Khramtsov, and
I A Morozov, and
E P Senchenkov, and
V M Zemskov
July 1988,
Atherosclerosis,
V V Shcherbukhin, and
A V Khramtsov, and
I A Morozov, and
E P Senchenkov, and
V M Zemskov
June 1980,
Mechanisms of ageing and development,
V V Shcherbukhin, and
A V Khramtsov, and
I A Morozov, and
E P Senchenkov, and
V M Zemskov
January 1980,
Archives d'anatomie microscopique et de morphologie experimentale,
V V Shcherbukhin, and
A V Khramtsov, and
I A Morozov, and
E P Senchenkov, and
V M Zemskov
January 1989,
Farmakologiia i toksikologiia,
