-transparent.png){kind=logo}
Thirteen women with infertility thought due to anovulation were treated with LRH. Etiologic diagnoses of amenorrhea included hypothalamic or "idiopathic" and PCOD. All patients had normal gonadotropins and otherwise normal endocrinologic and infertility evaluations; none had ovulated with clomiphene. Patients were studied for six 35 day cycles, single blind, and received LRH or placebo by subcutaneous injections for 28 days/cycle (LRH dosage 1.0 mg 2 or 3 times each day). Frequent assessments of physical status, cervical mucus, vaginal cytology, and serum LH, FSH, estrogen, and progesterone were performed. Ovulation was documented by basal temperature, serum progesterone and, on occasion, endometrial biopsy. Follow-up was continued for 6 months after therapy. Of the 13 patients treated, eight have ovulated and five have conceived. There were no complications of therapy.
C B Hammond, and
R H Wiebe, and
A F Haney, and
S G Yancy
August 1975,
Fertility and sterility,
C B Hammond, and
R H Wiebe, and
A F Haney, and
S G Yancy
January 1976,
Fertility and sterility,
C B Hammond, and
R H Wiebe, and
A F Haney, and
S G Yancy
June 1974,
Fertility and sterility,
C B Hammond, and
R H Wiebe, and
A F Haney, and
S G Yancy
January 1979,
Obstetrics and gynecology,
C B Hammond, and
R H Wiebe, and
A F Haney, and
S G Yancy
September 1972,
Lancet (London, England),
C B Hammond, and
R H Wiebe, and
A F Haney, and
S G Yancy
October 1974,
American journal of obstetrics and gynecology,
C B Hammond, and
R H Wiebe, and
A F Haney, and
S G Yancy
April 1984,
The New England journal of medicine,
C B Hammond, and
R H Wiebe, and
A F Haney, and
S G Yancy
November 1988,
Zhonghua fu chan ke za zhi,
C B Hammond, and
R H Wiebe, and
A F Haney, and
S G Yancy
July 1974,
Fertility and sterility,
C B Hammond, and
R H Wiebe, and
A F Haney, and
S G Yancy
December 1985,
Fertility and sterility,
