Biomaterial Database

[Immunochemical determination of neurospecific beta 2-globulin in cerebrospinal fluid in mental disorders]. 1985

V K Buĭlov, and N D Lakosina, and Iu S Tamarinov, and A A Terent'ev

Immunochemical identification of neurospecific beta 2-globulin (N beta G) in the cerebrospinal fluid (CSF) of mentally healthy subjects and mental patients showed its immunochemical identity in both group. A comparative immunochemical analysis revealed considerable differences in N beta G levels in the CSF in patients with neuropsychic diseases as compared with the control group. The content of N beta G was found to vary in different psychopathological syndromes. It is suggested that variations in N beta G levels in the CSF may be related to psychomotor activity.

UI	MeSH Term	Description	Entries
D007122	Immunoelectrophoresis	A technique that combines protein electrophoresis and double immunodiffusion. In this procedure proteins are first separated by gel electrophoresis (usually agarose), then made visible by immunodiffusion of specific antibodies. A distinct elliptical precipitin arc results for each protein detectable by the antisera.
D008875	Middle Aged	An adult aged 45 - 64 years.	Middle Age
D009440	Neurasthenia	A mental disorder characterized by chronic fatigue and concomitant physiologic symptoms.	Bodily Distress Disorder,Neurasthenic Neuroses,Neuroses, Neurasthenic,Bodily Distress Disorders,Disorder, Bodily Distress,Distress Disorder, Bodily
D009497	Neurotic Disorders	Disorders in which the symptoms are distressing to the individual and recognized by him or her as being unacceptable. Social relationships may be greatly affected but usually remain within acceptable limits. The disturbance is relatively enduring or recurrent without treatment.	Neuroses,Psychoneuroses,Disorder, Neurotic,Disorders, Neurotic,Neurotic Disorder
D001883	Borderline Personality Disorder	A personality disorder marked by a pattern of instability of interpersonal relationships, self-image, and affects, and marked impulsivity beginning by early adulthood and present in a variety of contexts. (DSM-IV)	Personality Disorder, Borderline,Disorder, Borderline Personality,Borderline Personality Disorders,Disorders, Borderline Personality,Personality Disorders, Borderline
D006801	Humans	Members of the species Homo sapiens.	Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000328	Adult	A person having attained full growth or maturity. Adults are of 19 through 44 years of age. For a person between 19 and 24 years of age, YOUNG ADULT is available.	Adults
D001523	Mental Disorders	Psychiatric illness or diseases manifested by breakdowns in the adaptational process expressed primarily as abnormalities of thought, feeling, and behavior producing either distress or impairment of function.	Mental Illness,Psychiatric Diseases,Psychiatric Disorders,Psychiatric Illness,Behavior Disorders,Diagnosis, Psychiatric,Mental Disorders, Severe,Psychiatric Diagnosis,Illness, Mental,Mental Disorder,Mental Disorder, Severe,Mental Illnesses,Psychiatric Disease,Psychiatric Disorder,Psychiatric Illnesses,Severe Mental Disorder,Severe Mental Disorders
D001613	beta 2-Microglobulin	An 11-kDa protein associated with the outer membrane of many cells including LYMPHOCYTES. It is the small subunit of MHC CLASS I MOLECULES. Association with beta 2-microglobulin is generally required for the transport of class I heavy chains from the endoplasmic reticulum to the cell surface. Beta 2-microglobulin is present in small amounts in serum, CEREBROSPINAL FLUID, and urine of healthy individuals, and to a much greater degree in the urine and plasma of patients with tubular PROTEINURIA, renal failure, or kidney transplants.	Thymotaxin,beta 2 Microglobulin
D012559	Schizophrenia	A severe emotional disorder of psychotic depth characteristically marked by a retreat from reality with delusion formation, HALLUCINATIONS, emotional disharmony, and regressive behavior.	Dementia Praecox,Schizophrenic Disorders,Disorder, Schizophrenic,Disorders, Schizophrenic,Schizophrenias,Schizophrenic Disorder