Biomaterial Database

Effect of ambroxol on human phagocytic cell function. 1985

F Capsoni, and A M Ongari, and F Minonzio, and A Lazzarin, and G Zavattini

The in vitro effects of ambroxol on phagocytic and microbicidal activities of human neutrophils and monocytes have been studied. Preincubation of neutrophils with ambroxol (10 to 100 ng/ml) had no effect on their phagocytic or microbicidal capacities. On the other hand, when monocytes were preincubated for 24 hours with ambroxol a significant increase of their microbicidal activity was observed, without effect on the phagocytic properties.

UI	MeSH Term	Description	Entries
D009504	Neutrophils	Granular leukocytes having a nucleus with three to five lobes connected by slender threads of chromatin, and cytoplasm containing fine inconspicuous granules and stainable by neutral dyes.	LE Cells,Leukocytes, Polymorphonuclear,Polymorphonuclear Leukocytes,Polymorphonuclear Neutrophils,Neutrophil Band Cells,Band Cell, Neutrophil,Cell, LE,LE Cell,Leukocyte, Polymorphonuclear,Neutrophil,Neutrophil Band Cell,Neutrophil, Polymorphonuclear,Polymorphonuclear Leukocyte,Polymorphonuclear Neutrophil
D010587	Phagocytosis	The engulfing and degradation of microorganisms; other cells that are dead, dying, or pathogenic; and foreign particles by phagocytic cells (PHAGOCYTES).	Phagocytoses
D001964	Bromhexine	A mucolytic agent used in the treatment of respiratory disorders associated with viscid or excessive mucus. (From Martindale, The Extra Pharmacopoeia, 30th ed, p744)	Aparsonin,Bisolvon,Bromhexin,Bromhexin BC,Bromhexin Berlin-Chemie,Bromhexin-ratiopharm,Bromhexine Hydrochloride,Bromhexine Monohydrochloride,Brotussol,Darolan,Dur-Elix,Famel Bromhexine,Flegamin,Flubron,Hustentabs-ratiopharm,Mucohexine,NA-274,Quentan,Tesacof,bromhexin von ct,BC, Bromhexin,Bromhexin Berlin Chemie,Bromhexin BerlinChemie,Bromhexin ratiopharm,Bromhexine, Famel,Bromhexinratiopharm,Dur Elix,DurElix,Hustentabs ratiopharm,Hustentabsratiopharm,Hydrochloride, Bromhexine,Monohydrochloride, Bromhexine,NA 274,NA274,ct, bromhexin von,von ct, bromhexin
D002176	Candida albicans	A unicellular budding fungus which is the principal pathogenic species causing CANDIDIASIS (moniliasis).	Candida albicans var. stellatoidea,Candida stellatoidea,Dematium albicans,Monilia albicans,Myceloblastanon albicans,Mycotorula albicans,Parasaccharomyces albicans,Procandida albicans,Procandida stellatoidea,Saccharomyces albicans,Syringospora albicans
D006801	Humans	Members of the species Homo sapiens.	Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000551	Ambroxol	A metabolite of BROMHEXINE that stimulates mucociliary action and clears the air passages in the respiratory tract. It is usually administered as the hydrochloride.	Bromhexine Metabolite VIII,4-(((2-Amino-3,5-dibromophenyl)methyl)amino)cyclohexanol,AMBROPP,Abrohexal,Ambril,Ambro-Puren,Ambrobeta,Ambrofur,Ambrohexal,Ambrolitic,Ambrolös,Ambroten,Ambroxin,Ambroxocompren,Bisolvon AM,Bronchopront,Bronchowern,Broxol,Contac Husten-Trunk,Dinobroxol,Duramucal,Ebromin,Expeflen,Expit,Farmabroxol,Flavamed,Frenopect,Gelopol,Larylin Husten-Löser,Lasolvan,Mibrox,Motosol,Muco-Fips,Mucosolvan,Mucotablin,NA-872,Pect Hustenlöser,Pulmonal S,Pädiamuc,Ringelheimer Pulmonal,Sekretovit,Surbronc,Therapin Hustenlöser,stas-Hustenlöser,AM, Bisolvon,Ambro Puren,AmbroPuren,Contac Husten Trunk,Contac HustenTrunk,Hustenlöser, Pect,Hustenlöser, Therapin,Larylin Husten Löser,Larylin HustenLöser,Metabolite VIII, Bromhexine,Muco Fips,MucoFips,NA 872,NA872,Pulmonal, Ringelheimer,stas Hustenlöser,stasHustenlöser
D013997	Time Factors	Elements of limited time intervals, contributing to particular results or situations.	Time Series,Factor, Time,Time Factor
D066298	In Vitro Techniques	Methods to study reactions or processes taking place in an artificial environment outside the living organism.	In Vitro Test,In Vitro Testing,In Vitro Tests,In Vitro as Topic,In Vitro,In Vitro Technique,In Vitro Testings,Technique, In Vitro,Techniques, In Vitro,Test, In Vitro,Testing, In Vitro,Testings, In Vitro,Tests, In Vitro,Vitro Testing, In