[Changes in water-electrolyte balance and central hemodynamics in hypertensive crises]. 1985

E M Evsikov, and V A Liusov, and V I Kharchenko

Sodium, potassium and water distribution, central hemodynamic parameters, and plasma renin activity and aldosterone levels were examined in 48 patients with stable essential hypertension, including 10 males and 11 females with hypertensive crises aggravating the course of the disease, and in 18 controls. The individuals showing signs of heart and renal failure were excluded from the analysis. In female patients, the crise pattern of the disease was associated with marked changes of sodium metabolism, namely, raised extracellular fluid and plasma sodium levels, the patients with the crises having a more severe course of the disease, with higher, as compared to those of crises-free patients, total peripheral resistance and lower cardiac output values. In female patients with the crises, plasma renin activity was reduced 3.3-fold, while aldosterone levels remained unchanged, as compared to the levels of crises-free women. A direct correlation was demonstrated between the recurrence of the crises and total peripheral resistance. Causes of sodium retention in female patients with the crises are discussed.

UI MeSH Term Description Entries
D006955 Hypernatremia Excessive amount of sodium in the blood. (Dorland, 27th ed) Hypernatremias
D006974 Hypertension, Malignant A condition of markedly elevated BLOOD PRESSURE with DIASTOLIC PRESSURE usually greater than 120 mm Hg. Malignant hypertension is characterized by widespread vascular damage, PAPILLEDEMA, retinopathy, HYPERTENSIVE ENCEPHALOPATHY, and renal dysfunction. Malignant Hypertension
D007008 Hypokalemia Abnormally low potassium concentration in the blood. It may result from potassium loss by renal secretion or by the gastrointestinal route, as by vomiting or diarrhea. It may be manifested clinically by neuromuscular disorders ranging from weakness to paralysis, by electrocardiographic abnormalities (depression of the T wave and elevation of the U wave), by renal disease, and by gastrointestinal disorders. (Dorland, 27th ed) Hypopotassemia,Hypokalemias,Hypopotassemias
D008297 Male Males
D008875 Middle Aged An adult aged 45 - 64 years. Middle Age
D011188 Potassium An element in the alkali group of metals with an atomic symbol K, atomic number 19, and atomic weight 39.10. It is the chief cation in the intracellular fluid of muscle and other cells. Potassium ion is a strong electrolyte that plays a significant role in the regulation of fluid volume and maintenance of the WATER-ELECTROLYTE BALANCE.
D012083 Renin A highly specific (Leu-Leu) endopeptidase that generates ANGIOTENSIN I from its precursor ANGIOTENSINOGEN, leading to a cascade of reactions which elevate BLOOD PRESSURE and increase sodium retention by the kidney in the RENIN-ANGIOTENSIN SYSTEM. The enzyme was formerly listed as EC 3.4.99.19. Angiotensin-Forming Enzyme,Angiotensinogenase,Big Renin,Cryorenin,Inactive Renin,Pre-Prorenin,Preprorenin,Prorenin,Angiotensin Forming Enzyme,Pre Prorenin,Renin, Big,Renin, Inactive
D005260 Female Females
D006439 Hemodynamics The movement and the forces involved in the movement of the blood through the CARDIOVASCULAR SYSTEM. Hemodynamic
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man

Related Publications

E M Evsikov, and V A Liusov, and V I Kharchenko
February 1969, Vrachebnoe delo,
E M Evsikov, and V A Liusov, and V I Kharchenko
January 1982, Hypertension (Dallas, Tex. : 1979),
E M Evsikov, and V A Liusov, and V I Kharchenko
November 1961, Der Anaesthesist,
E M Evsikov, and V A Liusov, and V I Kharchenko
January 1991, Zeitschrift fur Gerontologie,
E M Evsikov, and V A Liusov, and V I Kharchenko
January 1985, Sovetskaia meditsina,
E M Evsikov, and V A Liusov, and V I Kharchenko
August 1989, Boletin medico del Hospital Infantil de Mexico,
E M Evsikov, and V A Liusov, and V I Kharchenko
July 1981, Kardiologiia,
E M Evsikov, and V A Liusov, and V I Kharchenko
April 1952, Boletin de la Asociacion Medica de Puerto Rico,
E M Evsikov, and V A Liusov, and V I Kharchenko
January 1962, Revista cubana de medicina,
E M Evsikov, and V A Liusov, and V I Kharchenko
November 1961, Wisconsin medical journal,
Copied contents to your clipboard!