Biomaterial Database

Out-patient treatment of psoriasis: short contact and overnight dithranol therapy compared. 1985

S K Jones, and W C Campbell, and R M Mackie

Short contact (30 min) and overnight therapy with 1%, 2% and 3% dithranol in an ointment base were compared in 30 out-patients with plaque psoriasis. Both regimes produced significant clearing, there being no statistically significant difference between the two. There were three withdrawals from each group. The remaining 12 patients on the 30 min regime found it both effective and practical. It is therefore a useful alternative regime for out-patient dithranol therapy.

UI	MeSH Term	Description	Entries
D011565	Psoriasis	A common genetically determined, chronic, inflammatory skin disease characterized by rounded erythematous, dry, scaling patches. The lesions have a predilection for nails, scalp, genitalia, extensor surfaces, and the lumbosacral region. Accelerated epidermopoiesis is considered to be the fundamental pathologic feature in psoriasis.	Palmoplantaris Pustulosis,Pustular Psoriasis of Palms and Soles,Pustulosis Palmaris et Plantaris,Pustulosis of Palms and Soles,Psoriases
D011897	Random Allocation	A process involving chance used in therapeutic trials or other research endeavor for allocating experimental subjects, human or animal, between treatment and control groups, or among treatment groups. It may also apply to experiments on inanimate objects.	Randomization,Allocation, Random
D002986	Clinical Trials as Topic	Works about pre-planned studies of the safety, efficacy, or optimum dosage schedule (if appropriate) of one or more diagnostic, therapeutic, or prophylactic drugs, devices, or techniques selected according to predetermined criteria of eligibility and observed for predefined evidence of favorable and unfavorable effects. This concept includes clinical trials conducted both in the U.S. and in other countries.	Clinical Trial as Topic
D004334	Drug Administration Schedule	Time schedule for administration of a drug in order to achieve optimum effectiveness and convenience.	Administration Schedule, Drug,Administration Schedules, Drug,Drug Administration Schedules,Schedule, Drug Administration,Schedules, Drug Administration
D006801	Humans	Members of the species Homo sapiens.	Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000553	Ambulatory Care	Health care services provided to patients on an ambulatory basis, rather than by admission to a hospital or other health care facility. The services may be a part of a hospital, augmenting its inpatient services, or may be provided at a free-standing facility.	Outpatient Care,Outpatient Health Services,Clinic Visits,Health Services, Outpatient,Outpatient Services,Services, Outpatient Health,Urgent Care,Care, Ambulatory,Care, Outpatient,Care, Urgent,Cares, Urgent,Clinic Visit,Health Service, Outpatient,Outpatient Health Service,Outpatient Service,Service, Outpatient,Service, Outpatient Health,Services, Outpatient,Urgent Cares,Visit, Clinic,Visits, Clinic
D000873	Anthracenes	A group of compounds with three aromatic rings joined in linear arrangement.
D000875	Anthralin	An anthracene derivative that disrupts function and structure of MITOCHONDRIA and is used for the treatment of DERMATOSES, especially PSORIASIS. It may cause FOLLICULITIS.	1,8-Dihydroxy-9-anthrone,Dithranol,1,8,9-Anthracenetriol,1,8-Dihydroxy-9(10H)-anthracenone,Anthraforte,Anthranol,Cignolin,Cygnoline,Dihydroxyanthranol,Dithrocream,Ditranol FNA,Lasan,Micanol,Psoradrate,Psoricrème,1,8 Dihydroxy 9 anthrone,FNA, Ditranol
D013997	Time Factors	Elements of limited time intervals, contributing to particular results or situations.	Time Series,Factor, Time,Time Factor