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Overwhelming postsplenectomy infection (OPSI) due to group B streptococcus developed in an insulin-dependent diabetic patient. The illness began with nonspecific symptoms, followed rapidly by hypotension and disseminated intravascular coagulation. The early institution of appropriate antibiotics, fluid replacement and pressor agents resulted in a favorable clinical outcome. The association of group B streptococcal infection and diabetes mellitus is discussed. The defects in normal host defenses associated with asplenic state and diabetes mellitus are further emphasized. This is the first case report linking the association of OPSI, diabetes mellitus and group B streptococcal septicemia.
H R Fish, and
J K Chia, and
K M Shakir
December 1979,
Southern medical journal,
H R Fish, and
J K Chia, and
K M Shakir
June 1980,
Revista clinica espanola,
H R Fish, and
J K Chia, and
K M Shakir
June 2016,
Journal of the American Geriatrics Society,
H R Fish, and
J K Chia, and
K M Shakir
October 1980,
Minerva pediatrica,
H R Fish, and
J K Chia, and
K M Shakir
January 1981,
Revista espanola de cardiologia,
H R Fish, and
J K Chia, and
K M Shakir
May 1999,
Journal of the American Geriatrics Society,
H R Fish, and
J K Chia, and
K M Shakir
October 1987,
Revista espanola de las enfermedades del aparato digestivo,
H R Fish, and
J K Chia, and
K M Shakir
January 1984,
Revista clinica espanola,
H R Fish, and
J K Chia, and
K M Shakir
January 1970,
Acta pathologica et microbiologica Scandinavica. Section B: Microbiology and immunology,
H R Fish, and
J K Chia, and
K M Shakir
December 1970,
Monatsschrift fur Kinderheilkunde,
