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Platelet sensitivity to adenosine diphosphate (ADP) and to prostacyclin (PGI2) was studied in normal and diabetic pregnant women. The threshold concentrations of ADP inducing the second phase of aggregation were used to determine the platelet sensitivity to PGI2. The sensitivity of platelets to ADP increased in both groups in the second trimester, thereafter it decreased both in normal and diabetic pregnancies. In contrast, sensitivity to PGI2 increased in the last trimester of pregnancy. No difference could be observed between diabetic and normal groups. The similarity of the results between the two groups could be explained by the normoglycaemic state of well-controlled diabetic pregnant women.
G Gerö, and
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K Tihanyi, and
J Oláh, and
J Demeter, and
I Gáti
August 1982,
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G Gerö, and
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May 1985,
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G Gerö, and
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J Oláh, and
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I Gáti
October 1986,
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G Gerö, and
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J Oláh, and
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I Gáti
October 1983,
Lancet (London, England),
G Gerö, and
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I Gáti
July 1981,
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G Gerö, and
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K Tihanyi, and
J Oláh, and
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I Gáti
November 1990,
Diabetes research (Edinburgh, Scotland),
G Gerö, and
I Rákóczi, and
K Tihanyi, and
J Oláh, and
J Demeter, and
I Gáti
August 1981,
Thrombosis and haemostasis,
G Gerö, and
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K Tihanyi, and
J Oláh, and
J Demeter, and
I Gáti
November 1989,
Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme,
G Gerö, and
I Rákóczi, and
K Tihanyi, and
J Oláh, and
J Demeter, and
I Gáti
January 1965,
Nature,
G Gerö, and
I Rákóczi, and
K Tihanyi, and
J Oláh, and
J Demeter, and
I Gáti
January 1999,
Platelets,
