BIOMAT Database Logo BIOMAT Database Logo

HLA matching and cadaver kidney transplantation--status 1984. 1985

G Opelz

The effect of HLA matching on cadaver kidney graft survival was analysed in over 9000 transplants. Matching for HLA-A and -B accounted for an improvement of 8% in the one-year survival rate, matching for HLA-DR for 10%, and matching for HLA-B + DR for 19%. The matching effect of the HLA-B and HLA-DR loci was additive. Patients without pre-transplant transfusions had lower graft survival rates than transfused patients, even if their grafts were HLA matched. The highest success rate was obtained in transfused recipients who received HLA matched kidneys.

UI MeSH Term Description Entries
D002102 Cadaver A dead body, usually a human body. Corpse,Cadavers,Corpses
D006085 Graft Survival The survival of a graft in a host, the factors responsible for the survival and the changes occurring within the graft during growth in the host. Graft Survivals,Survival, Graft,Survivals, Graft
D006650 Histocompatibility Testing Identification of the major histocompatibility antigens of transplant DONORS and potential recipients, usually by serological tests. Donor and recipient pairs should be of identical ABO blood group, and in addition should be matched as closely as possible for HISTOCOMPATIBILITY ANTIGENS in order to minimize the likelihood of allograft rejection. (King, Dictionary of Genetics, 4th ed) Crossmatching, Tissue,HLA Typing,Tissue Typing,Crossmatchings, Tissue,HLA Typings,Histocompatibility Testings,Testing, Histocompatibility,Testings, Histocompatibility,Tissue Crossmatching,Tissue Crossmatchings,Tissue Typings,Typing, HLA,Typing, Tissue,Typings, HLA,Typings, Tissue
D006680 HLA Antigens Antigens determined by leukocyte loci found on chromosome 6, the major histocompatibility loci in humans. They are polypeptides or glycoproteins found on most nucleated cells and platelets, determine tissue types for transplantation, and are associated with certain diseases. Human Leukocyte Antigen,Human Leukocyte Antigens,Leukocyte Antigens,HL-A Antigens,Antigen, Human Leukocyte,Antigens, HL-A,Antigens, HLA,Antigens, Human Leukocyte,Antigens, Leukocyte,HL A Antigens,Leukocyte Antigen, Human,Leukocyte Antigens, Human
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D016030 Kidney Transplantation The transference of a kidney from one human or animal to another. Grafting, Kidney,Renal Transplantation,Transplantation, Kidney,Transplantation, Renal,Kidney Grafting,Kidney Transplantations,Renal Transplantations,Transplantations, Kidney,Transplantations, Renal

Related Publications

G Opelz
Influence of HLA-DR matching in cadaver kidney transplantation in Swisstransplant.
March 1979, Transplantation proceedings,
G Opelz
Dr matching and cadaver kidney transplantation.
January 1982, Transplantation,
G Opelz
HLA matching for improved cadaver kidney allocation.
November 1994, Current opinion in nephrology and hypertension,
G Opelz
HLA-DR antigen matching in cadaver renal transplantation.
April 1978, Lancet (London, England),
G Opelz
HLA matching for kidney transplantation.
December 2004, Human immunology,
G Opelz
HLA and cross-reactive antigen group matching for cadaver kidney allocation.
October 1997, Transplantation,
G Opelz
Feasibility of HLA haplotype matching of cadaver kidney donors and recipients.
December 1977, Transplantation proceedings,
G Opelz
Successful DR-incompatible cadaver kidney transplantation. Combined effect of HLA A and B matching and blood transfusion.
December 1984, Transplantation,
G Opelz
Equity in cadaver kidney allocation does not imply neglecting HLA matching.
January 2000, Transplant international : official journal of the European Society for Organ Transplantation,
G Opelz
Diminishing significance of HLA matching in kidney transplantation.
September 2004, American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons,
Copied contents to your clipboard!