Biomaterial Database

[Risk of infection of central venous catheters in childhood--results of a prospective study]. 1985

M Höllwarth, and R Wildburger, and B Sixl-Voigt

Contamination rate of 228 central venous catheters and incidence of catheter related septicaemia were studied prospectively in 133 children (98 newborn, 11 infants, 14 children). An exact protocol determined all details related to catheter insertion, subcutaneous tunneling, local disinfection with polyvinyliodide ointment, procedure of mixing the solutions for parenteral feeding, etc. Culture swabs were taken routinely from the feeding solutions and the infusion device. After removing the catheter additional bacteriological studies were performed from the catheter tip and the skin at the site of insertion. Although the results showed a low incidence of contamination at the infusion device (1.1%) and the parenteral solutions (3.6%), the contamination rate of the skin (31.6%) and the catheter tip (35.3%) were exceedingly high. While the bacteriological studies of the infusion and the infusion set showed mostly apathogenous cocci, staphylococci epidermidis and staphylococci aureus were predominant on the skin and the catheter tip. Despite this high contamination rate a catheter related septicaemia was suspected in 17 cases only (7.4%). In six catheters (2.6%) the infection was confirmed by bacteriological results which always showed the typical micro-organisms found on the skin at the catheter insertion site. Therefore, the most important infection route seems to be the way from the skin to the catheter tip. Despite negative bacteriological results in the other eleven catheters a septicaemia was highly suspected on the basis of the laboratory findings.(ABSTRACT TRUNCATED AT 250 WORDS)

UI	MeSH Term	Description	Entries
D007223	Infant	A child between 1 and 23 months of age.	Infants
D007231	Infant, Newborn	An infant during the first 28 days after birth.	Neonate,Newborns,Infants, Newborn,Neonates,Newborn,Newborn Infant,Newborn Infants
D007263	Infusions, Parenteral	The administration of liquid medication, nutrient, or other fluid through some other route than the alimentary canal, usually over minutes or hours, either by gravity flow or often by infusion pumping.	Intra-Abdominal Infusions,Intraperitoneal Infusions,Parenteral Infusions,Peritoneal Infusions,Infusion, Intra-Abdominal,Infusion, Intraperitoneal,Infusion, Parenteral,Infusion, Peritoneal,Infusions, Intra-Abdominal,Infusions, Intraperitoneal,Infusions, Peritoneal,Intra Abdominal Infusions,Intra-Abdominal Infusion,Intraperitoneal Infusion,Parenteral Infusion,Peritoneal Infusion
D011446	Prospective Studies	Observation of a population for a sufficient number of persons over a sufficient number of years to generate incidence or mortality rates subsequent to the selection of the study group.	Prospective Study,Studies, Prospective,Study, Prospective
D002408	Catheters, Indwelling	Catheters designed to be left within an organ or passage for an extended period of time.	Implantable Catheters,In-Dwelling Catheters,Catheter, In-Dwelling,Catheter, Indwelling,Catheters, In-Dwelling,In Dwelling Catheters,In-Dwelling Catheter,Indwelling Catheter,Indwelling Catheters
D003428	Cross Infection	Any infection which a patient contracts in a health-care institution.	Hospital Infections,Nosocomial Infections,Health Care Associated Infection,Health Care Associated Infections,Healthcare Associated Infections,Infection, Cross,Infections, Hospital,Infections, Nosocomial,Cross Infections,Healthcare Associated Infection,Hospital Infection,Infection, Healthcare Associated,Infection, Hospital,Infection, Nosocomial,Infections, Cross,Infections, Healthcare Associated,Nosocomial Infection
D006801	Humans	Members of the species Homo sapiens.	Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D001431	Bacteriological Techniques	Techniques used in studying bacteria.	Bacteriologic Technic,Bacteriologic Technics,Bacteriologic Techniques,Bacteriological Technique,Technic, Bacteriological,Technics, Bacteriological,Technique, Bacteriological,Techniques, Bacteriological,Bacteriologic Technique,Bacteriological Technic,Bacteriological Technics,Technic, Bacteriologic,Technics, Bacteriologic,Technique, Bacteriologic,Techniques, Bacteriologic
D012306	Risk	The probability that an event will occur. It encompasses a variety of measures of the probability of a generally unfavorable outcome.	Relative Risk,Relative Risks,Risk, Relative,Risks,Risks, Relative
D013203	Staphylococcal Infections	Infections with bacteria of the genus STAPHYLOCOCCUS.	Infections, Staphylococcal,Staphylococcus aureus Infection,Staphylococcal Infection,Staphylococcus aureus Infections