Proportional counter dosimetry and microdosimetry for radiotherapy with multiple pion beams. 1985

H Schuhmacher, and H G Menzel, and H Blattmann, and H Muth

At the Swiss Institute for Nuclear Research (SIN) cancer patients are irradiated with negatively charged pi mesons using a 60-beam medical pion generator, the Piotron. A low-pressure tissue-equivalent proportional counter was used to measure absorbed dose and microdosimetric spectra. A method was developed to allow discrimination of events from different beam components, i.e., beam contamination (electrons and muons), pions in flight, and stopping pions. Measurements were performed along the axis and at lateral distances off one of these identical pion beams. The marked changes of total microdosimetric spectra with depth in phantom detected in earlier measurements are mainly due to large variations in the dose contributions of the beam components and much less to changes in the shapes of the individual microdosimetric spectra. The single beam measurements were used to calculate three-dimensional distributions of absorbed dose and of dose mean lineal energy, yD, for dynamic patient irradiations. Within the whole target volume yD remains nearly constant when irradiated with all 60 beams, whereas considerable changes were found for irradiations with 31 beams coming from a semicircle. Both size and shape of target volumes influence yD, the maximum values ranging from 30 to 45 keV/micron.

UI MeSH Term Description Entries
D008651 Mesons Short-lived elementary particles found in cosmic radiation or produced from nuclear disintegration. Their mass is between that of protons and electrons and they can be negative, positive, or neutral. pi-Mesons (pions) are heavier than mu-mesons (muons) and are proposed for cancer radiotherapy because their capture and disintegration by matter produces powerful, but short-lived, secondary radiation. Muons,Pions,mu-Mesons,pi-Mesons,Meson,Muon,Pion,mu Mesons,mu-Meson,pi Mesons,pi-Meson
D009369 Neoplasms New abnormal growth of tissue. Malignant neoplasms show a greater degree of anaplasia and have the properties of invasion and metastasis, compared to benign neoplasms. Benign Neoplasm,Cancer,Malignant Neoplasm,Tumor,Tumors,Benign Neoplasms,Malignancy,Malignant Neoplasms,Neoplasia,Neoplasm,Neoplasms, Benign,Cancers,Malignancies,Neoplasias,Neoplasm, Benign,Neoplasm, Malignant,Neoplasms, Malignant
D011874 Radiometry The measurement of radiation by photography, as in x-ray film and film badge, by Geiger-Mueller tube, and by SCINTILLATION COUNTING. Geiger-Mueller Counters,Nuclear Track Detection,Radiation Dosimetry,Dosimetry, Radiation,Geiger Counter,Geiger-Mueller Counter Tube,Geiger-Mueller Probe,Geiger-Mueller Tube,Radiation Counter,Counter Tube, Geiger-Mueller,Counter Tubes, Geiger-Mueller,Counter, Geiger,Counter, Radiation,Counters, Geiger,Counters, Geiger-Mueller,Counters, Radiation,Detection, Nuclear Track,Dosimetries, Radiation,Geiger Counters,Geiger Mueller Counter Tube,Geiger Mueller Counters,Geiger Mueller Probe,Geiger Mueller Tube,Geiger-Mueller Counter Tubes,Geiger-Mueller Probes,Geiger-Mueller Tubes,Probe, Geiger-Mueller,Probes, Geiger-Mueller,Radiation Counters,Radiation Dosimetries,Tube, Geiger-Mueller,Tube, Geiger-Mueller Counter,Tubes, Geiger-Mueller,Tubes, Geiger-Mueller Counter
D011879 Radiotherapy Dosage The total amount of radiation absorbed by tissues as a result of radiotherapy. Dosage, Radiotherapy,Dosages, Radiotherapy,Radiotherapy Dosages
D011882 Radiotherapy, High-Energy Radiotherapy using high-energy (megavolt or higher) ionizing radiation. Types of radiation include gamma rays, produced by a radioisotope within a teletherapy unit; x-rays, electrons, protons, alpha particles (helium ions) and heavy charged ions, produced by particle acceleration; and neutrons and pi-mesons (pions), produced as secondary particles following bombardment of a target with a primary particle. Megavolt Radiotherapy,High-Energy Radiotherapy,Radiotherapy, Megavolt,High Energy Radiotherapy,Radiotherapy, High Energy
D004601 Elementary Particles Individual components of atoms, usually subatomic; subnuclear particles are usually detected only when the atomic nucleus decays and then only transiently, as most of them are unstable, often yielding pure energy without substance, i.e., radiation. Baryons,Fundamental Particles,Baryon,Elementary Particle,Fundamental Particle,Particle, Elementary,Particle, Fundamental,Particles, Elementary,Particles, Fundamental
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man

Related Publications

H Schuhmacher, and H G Menzel, and H Blattmann, and H Muth
January 1977, Medical physics,
H Schuhmacher, and H G Menzel, and H Blattmann, and H Muth
September 1976, Nature,
H Schuhmacher, and H G Menzel, and H Blattmann, and H Muth
September 2000, Current pharmaceutical design,
H Schuhmacher, and H G Menzel, and H Blattmann, and H Muth
July 2021, Physics in medicine and biology,
H Schuhmacher, and H G Menzel, and H Blattmann, and H Muth
June 1969, Health physics,
H Schuhmacher, and H G Menzel, and H Blattmann, and H Muth
January 2002, Radiation protection dosimetry,
H Schuhmacher, and H G Menzel, and H Blattmann, and H Muth
March 1981, Physics in medicine and biology,
H Schuhmacher, and H G Menzel, and H Blattmann, and H Muth
July 2009, Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine,
H Schuhmacher, and H G Menzel, and H Blattmann, and H Muth
November 1982, International journal of radiation oncology, biology, physics,
H Schuhmacher, and H G Menzel, and H Blattmann, and H Muth
July 1972, Strahlentherapie,
Copied contents to your clipboard!