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Plasma prolactin concentrations were studied in 88 oophorectomised women who had been receiving mestranol or placebo for three to 11 years. Thirty one of them were also studied under basal conditions and by tests with thyrotrophin releasing hormone. Under basal conditions the mean prolactin concentration was higher in the oestrogen treated group but under non-rested, clinic conditions the difference was lost because of a rise in prolactin value in the placebo group only. Hence the groups showed a different prolactin response to the mild stress of clinic attendance but the same proportionate responsiveness to thyrotrophin releasing hormone. The data suggest that long term hormone replacement has no significant effect on circulating prolactin concentrations under non-rested, everyday conditions and that the prolactin stimulating effects of minor stress and oestrogen may share a similar mechanism.
D H Barlow, and
G H Beastall, and
H I Abdalla, and
J Elias-Jones, and
R Lindsay, and
D M Hart
January 1996,
Clinical endocrinology,
D H Barlow, and
G H Beastall, and
H I Abdalla, and
J Elias-Jones, and
R Lindsay, and
D M Hart
January 1997,
Gynecologic and obstetric investigation,
D H Barlow, and
G H Beastall, and
H I Abdalla, and
J Elias-Jones, and
R Lindsay, and
D M Hart
December 1982,
British journal of clinical pharmacology,
D H Barlow, and
G H Beastall, and
H I Abdalla, and
J Elias-Jones, and
R Lindsay, and
D M Hart
July 2002,
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D H Barlow, and
G H Beastall, and
H I Abdalla, and
J Elias-Jones, and
R Lindsay, and
D M Hart
September 1993,
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D H Barlow, and
G H Beastall, and
H I Abdalla, and
J Elias-Jones, and
R Lindsay, and
D M Hart
November 2010,
International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics,
D H Barlow, and
G H Beastall, and
H I Abdalla, and
J Elias-Jones, and
R Lindsay, and
D M Hart
December 2004,
Mayo Clinic proceedings,
D H Barlow, and
G H Beastall, and
H I Abdalla, and
J Elias-Jones, and
R Lindsay, and
D M Hart
January 1988,
The Journal of international medical research,
D H Barlow, and
G H Beastall, and
H I Abdalla, and
J Elias-Jones, and
R Lindsay, and
D M Hart
March 1998,
The journals of gerontology. Series A, Biological sciences and medical sciences,
D H Barlow, and
G H Beastall, and
H I Abdalla, and
J Elias-Jones, and
R Lindsay, and
D M Hart
July 1975,
The British journal of psychiatry : the journal of mental science,
