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Thirty-six menopausal women and 18 women with surgically-induced menopause were treated with a daily oral dose of 100 mg of veralipride for a period of 20 days followed by 10 days without therapy. Following 2 or 3 treatment periods, the drug was effective in 27 women from the first group and in 13 women from the second group. Six women had to discontinue therapy because of adverse effects. There was no significant variation in FSH or LH serum levels.
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