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We have prospectively studied the clinical data, prognostic factors and chronic liver sequelae in 68 patients who developed posttransfusion non-A, non-B hepatitis. The mean incubation period was 5.9 weeks with a range from 2.1 to 12 weeks; 63.5% of the patients were asymptomatic and 60.6% anicteric. The chronicity rate (elevated ALT values for a period of more than 6 months) was 67.6%. The chronicity rate of symptomatic hepatitis (95.5%) was significantly higher than that of asymptomatic hepatitis (54.5%) (P less than 0.01). Monophasic hepatitis, characterized by a rapid elevation in serum ALT followed by a rapid decline with no further fluctuations, had a chronicity rate (42.5%) significantly lower than polyphasic hepatitis (86.6%) (P less than 0.05) and plateau type hepatitis (94.4%) (P less than 0.01). Results of 35 liver biopsies carried out among 46 patients with elevated ALT after 6 months were as follows: chronic active hepatitis, 15 cases; prolonged acute hepatitis, 12 cases; chronic persistent hepatitis, 6 cases; posthepatitis liver changes, 1 case; and secondary hemosiderosis, 1 case.
R Barcena, and
E Suarez-Garcia, and
L A Gil, and
V F Moreira, and
F Garcia-Hoz, and
J M Milicua, and
D Boixeda de Miquel, and
L Ruiz del Arbol, and
J M Pascasio, and
A Garcia-Plaza
January 1983,
Vox sanguinis,
R Barcena, and
E Suarez-Garcia, and
L A Gil, and
V F Moreira, and
F Garcia-Hoz, and
J M Milicua, and
D Boixeda de Miquel, and
L Ruiz del Arbol, and
J M Pascasio, and
A Garcia-Plaza
October 1990,
Journal of medical virology,
R Barcena, and
E Suarez-Garcia, and
L A Gil, and
V F Moreira, and
F Garcia-Hoz, and
J M Milicua, and
D Boixeda de Miquel, and
L Ruiz del Arbol, and
J M Pascasio, and
A Garcia-Plaza
March 2000,
Zhonghua shi yan he lin chuang bing du xue za zhi = Zhonghua shiyan he linchuang bingduxue zazhi = Chinese journal of experimental and clinical virology,
R Barcena, and
E Suarez-Garcia, and
L A Gil, and
V F Moreira, and
F Garcia-Hoz, and
J M Milicua, and
D Boixeda de Miquel, and
L Ruiz del Arbol, and
J M Pascasio, and
A Garcia-Plaza
January 1991,
Gaceta medica de Mexico,
R Barcena, and
E Suarez-Garcia, and
L A Gil, and
V F Moreira, and
F Garcia-Hoz, and
J M Milicua, and
D Boixeda de Miquel, and
L Ruiz del Arbol, and
J M Pascasio, and
A Garcia-Plaza
May 1985,
Gastroenterology,
R Barcena, and
E Suarez-Garcia, and
L A Gil, and
V F Moreira, and
F Garcia-Hoz, and
J M Milicua, and
D Boixeda de Miquel, and
L Ruiz del Arbol, and
J M Pascasio, and
A Garcia-Plaza
January 1985,
Progress in clinical and biological research,
R Barcena, and
E Suarez-Garcia, and
L A Gil, and
V F Moreira, and
F Garcia-Hoz, and
J M Milicua, and
D Boixeda de Miquel, and
L Ruiz del Arbol, and
J M Pascasio, and
A Garcia-Plaza
August 1990,
[Zasshi] [Journal]. Nihon Kyobu Geka Gakkai,
R Barcena, and
E Suarez-Garcia, and
L A Gil, and
V F Moreira, and
F Garcia-Hoz, and
J M Milicua, and
D Boixeda de Miquel, and
L Ruiz del Arbol, and
J M Pascasio, and
A Garcia-Plaza
October 1984,
The American journal of gastroenterology,
R Barcena, and
E Suarez-Garcia, and
L A Gil, and
V F Moreira, and
F Garcia-Hoz, and
J M Milicua, and
D Boixeda de Miquel, and
L Ruiz del Arbol, and
J M Pascasio, and
A Garcia-Plaza
March 1993,
Hepatology (Baltimore, Md.),
R Barcena, and
E Suarez-Garcia, and
L A Gil, and
V F Moreira, and
F Garcia-Hoz, and
J M Milicua, and
D Boixeda de Miquel, and
L Ruiz del Arbol, and
J M Pascasio, and
A Garcia-Plaza
January 1983,
Vox sanguinis,
