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Serum aluminium concentrations and biopsy specimens of bone were examined in 56 patients with end stage chronic renal failure receiving maintenance haemodialysis. Deposits of aluminium in bone specimens were often associated with low bone formation with or without osteomalacia. Serum aluminium concentrations of greater than 3.7 mumol/l (10 micrograms/100 ml) indicated a high probability of deposits of aluminium in bone specimens, although high serum concentrations did not predict the type of renal bone disease. Biopsy of the bone is the best method of detecting aluminium intoxication of bone. A serum aluminium concentration of 3.7 mumol/l should be the threshold beyond which bone biopsy should be performed to confirm an overload of aluminium and identify histological bone changes induced by aluminium.
S A Charhon, and
P M Chavassieux, and
P J Meunier, and
M Accominotti
June 1985,
British medical journal (Clinical research ed.),
S A Charhon, and
P M Chavassieux, and
P J Meunier, and
M Accominotti
September 1985,
British medical journal (Clinical research ed.),
S A Charhon, and
P M Chavassieux, and
P J Meunier, and
M Accominotti
January 1982,
Lancet (London, England),
S A Charhon, and
P M Chavassieux, and
P J Meunier, and
M Accominotti
January 1984,
Mineral and electrolyte metabolism,
S A Charhon, and
P M Chavassieux, and
P J Meunier, and
M Accominotti
August 1987,
Lancet (London, England),
S A Charhon, and
P M Chavassieux, and
P J Meunier, and
M Accominotti
January 1985,
Proceedings of the European Dialysis and Transplant Association - European Renal Association. European Dialysis and Transplant Association - European Renal Association. Congress,
S A Charhon, and
P M Chavassieux, and
P J Meunier, and
M Accominotti
January 1984,
Virchows Archiv. A, Pathological anatomy and histopathology,
S A Charhon, and
P M Chavassieux, and
P J Meunier, and
M Accominotti
May 1996,
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association,
S A Charhon, and
P M Chavassieux, and
P J Meunier, and
M Accominotti
July 1998,
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association,
S A Charhon, and
P M Chavassieux, and
P J Meunier, and
M Accominotti
January 1985,
Zeitschrift fur medizinische Laboratoriumsdiagnostik,
