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We studied the distribution of 111In-labeled peritoneal mononuclear cells (PMC) in Sprague-Dawley rats with carcinosarcoma (CS) tumor. We obtained PMC from normal rats and rats pretreated with BCG or irradiated CS cells as antigenic stimulant. PMC were labeled in-vitro with 111In-oxine and transferred by tail-vein injection to rats bearing CS tumor. Twenty-four, 48 and 72 h after PMC transfer, we measured the accumulation of these cells in the CS tumor as a percentage of dose radioactivity per gram of tumor using an external gamma-ray camera. PMC from normal and BCG treated donor rats accumulated 0.4% and 0.46% dose per gram of CS tumor respectively. PMC from donor rats given killed CS cells accumulated significantly greater concentrations of 111In (0.79% dose per gram of CS tumor, P less than 0.025). Thus killed CS cells were able to sensitize the PMC of normal rats. 111In-oxine-labeling is an elegant procedure to study the distribution of mononuclear cells in tumors.
K Abreo, and
L M Lieberman, and
A V Moorthy
September 1987,
Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology,
K Abreo, and
L M Lieberman, and
A V Moorthy
January 1983,
Blood,
K Abreo, and
L M Lieberman, and
A V Moorthy
January 1985,
European journal of nuclear medicine,
K Abreo, and
L M Lieberman, and
A V Moorthy
January 1985,
Deutsche medizinische Wochenschrift (1946),
K Abreo, and
L M Lieberman, and
A V Moorthy
February 1987,
Nihon Geka Gakkai zasshi,
K Abreo, and
L M Lieberman, and
A V Moorthy
March 2005,
Neuroscience letters,
K Abreo, and
L M Lieberman, and
A V Moorthy
January 1987,
Contributions to nephrology,
K Abreo, and
L M Lieberman, and
A V Moorthy
December 1981,
Kaku igaku. The Japanese journal of nuclear medicine,
K Abreo, and
L M Lieberman, and
A V Moorthy
January 1985,
European journal of nuclear medicine,
K Abreo, and
L M Lieberman, and
A V Moorthy
January 1983,
European journal of nuclear medicine,
