-transparent.png){kind=logo}
The entry of environmental antigens into the lumen of the bursa of Fabricius was prevented by ligating the bursal duct prior to hatching (BDL: bursal duct ligation). The development of 'natural' serum agglutinins for bacteria and heteroerythrocytes was markedly suppressed by BDL. The antigen-specific recovery was observed by simultaneous administration of sterile antigens into the bursal lumen at the time of BDL. These results strongly suggest that the bursa of Fabricius is a major channel through which environmental antigens stimulate the immune system and induce the formation of 'natural' serum agglutinins.
Related Publications
S Ekino, and
K Suginohara, and
T Urano, and
H Fujii, and
K Matsuno, and
M Kotani
January 1985,
Advances in experimental medicine and biology,
S Ekino, and
K Suginohara, and
T Urano, and
H Fujii, and
K Matsuno, and
M Kotani
January 1975,
Nature,
S Ekino, and
K Suginohara, and
T Urano, and
H Fujii, and
K Matsuno, and
M Kotani
March 1993,
European journal of immunology,
S Ekino, and
K Suginohara, and
T Urano, and
H Fujii, and
K Matsuno, and
M Kotani
March 1978,
Journal of immunology (Baltimore, Md. : 1950),
S Ekino, and
K Suginohara, and
T Urano, and
H Fujii, and
K Matsuno, and
M Kotani
January 1971,
World's poultry science journal,
S Ekino, and
K Suginohara, and
T Urano, and
H Fujii, and
K Matsuno, and
M Kotani
January 1972,
Nature: New biology,
S Ekino, and
K Suginohara, and
T Urano, and
H Fujii, and
K Matsuno, and
M Kotani
July 1982,
Journal of the Royal Society of Medicine,
S Ekino, and
K Suginohara, and
T Urano, and
H Fujii, and
K Matsuno, and
M Kotani
January 1987,
Duodecim; laaketieteellinen aikakauskirja,
S Ekino, and
K Suginohara, and
T Urano, and
H Fujii, and
K Matsuno, and
M Kotani
February 1975,
Journal of the Reticuloendothelial Society,
S Ekino, and
K Suginohara, and
T Urano, and
H Fujii, and
K Matsuno, and
M Kotani
March 1959,
The American journal of anatomy,
