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Since it is now recognized that breast cancer is commonly a systemic disease at presentation, it is clear that local treatment is limited to providing local tumor control, and that effective systemic therapy is required for the eradication of micrometastatic disease. We here review the current status of conservative surgery and radiotherapy in the treatment of early breast cancer. Results from retrospective studies support the view that this combination is highly effective in achieving local control and maintaining good cosmetic results. Results at five and ten years from prospective trials indicate that survival using this approach is comparable to that of mastectomy. Though further follow-up is required, we do not believe that a large survival difference in favor of either approach will emerge.
J R Harris, and
A Recht, and
S Schnitt, and
J Connolly, and
B Silver, and
S Come, and
I C Henderson
March 1983,
Australasian radiology,
J R Harris, and
A Recht, and
S Schnitt, and
J Connolly, and
B Silver, and
S Come, and
I C Henderson
February 1994,
Annals of oncology : official journal of the European Society for Medical Oncology,
J R Harris, and
A Recht, and
S Schnitt, and
J Connolly, and
B Silver, and
S Come, and
I C Henderson
September 1995,
Zhonghua zhong liu za zhi [Chinese journal of oncology],
J R Harris, and
A Recht, and
S Schnitt, and
J Connolly, and
B Silver, and
S Come, and
I C Henderson
December 1984,
International journal of radiation oncology, biology, physics,
J R Harris, and
A Recht, and
S Schnitt, and
J Connolly, and
B Silver, and
S Come, and
I C Henderson
August 2005,
Zhonghua wai ke za zhi [Chinese journal of surgery],
J R Harris, and
A Recht, and
S Schnitt, and
J Connolly, and
B Silver, and
S Come, and
I C Henderson
January 1985,
Important advances in oncology,
J R Harris, and
A Recht, and
S Schnitt, and
J Connolly, and
B Silver, and
S Come, and
I C Henderson
January 1977,
Progress in clinical and biological research,
J R Harris, and
A Recht, and
S Schnitt, and
J Connolly, and
B Silver, and
S Come, and
I C Henderson
September 1992,
Nihon Geka Gakkai zasshi,
J R Harris, and
A Recht, and
S Schnitt, and
J Connolly, and
B Silver, and
S Come, and
I C Henderson
November 2000,
Minerva chirurgica,
J R Harris, and
A Recht, and
S Schnitt, and
J Connolly, and
B Silver, and
S Come, and
I C Henderson
November 1989,
La Radiologia medica,
