-transparent.png){kind=logo}
The distribution patterns of gangliosides and other major lipids in the monkey, rabbit and human brains with chronic organic mercury intoxication were examined. Various areas of the monkey brains were tested for alterations in the lipid composition in detail. Phosphatidylethanolamine and phosphatidylcholine slightly decreased, and sphingomyelin increased in all the areas tested of the intoxicated brains. The total ganglioside concentration was elevated in the frontal and basal ganglia gray matter tissues. In the percentage distribution of gangliosides, GD1b, GT1b and GQ1b (B pathway, [19, 20]) increased, while GM2, GM1 and GD1a (A pathway, [19, 20]) decreased. Similar ganglioside pattern changes were observed also in a human brain and in a rabbit brain with chronic organic mercury intoxication. The altered distribution patterns of gangliosides may be attributable to the proliferation of reactive astrocytes due to organic mercury.
S Ando, and
Y Toyoda, and
Y Nagai, and
F Ikuta
January 1969,
Voprosy meditsinskoi khimii,
S Ando, and
Y Toyoda, and
Y Nagai, and
F Ikuta
January 1986,
Japanese journal of ophthalmology,
S Ando, and
Y Toyoda, and
Y Nagai, and
F Ikuta
May 2001,
Acta paediatrica (Oslo, Norway : 1992),
S Ando, and
Y Toyoda, and
Y Nagai, and
F Ikuta
January 1957,
Acta Societatis Medicorum Upsaliensis,
S Ando, and
Y Toyoda, and
Y Nagai, and
F Ikuta
July 1988,
Journal of neurochemistry,
S Ando, and
Y Toyoda, and
Y Nagai, and
F Ikuta
March 1986,
Nippon Ganka Gakkai zasshi,
S Ando, and
Y Toyoda, and
Y Nagai, and
F Ikuta
August 1975,
Environmental research,
S Ando, and
Y Toyoda, and
Y Nagai, and
F Ikuta
January 1975,
Acta veterinaria Scandinavica,
S Ando, and
Y Toyoda, and
Y Nagai, and
F Ikuta
January 1946,
Federation proceedings,
S Ando, and
Y Toyoda, and
Y Nagai, and
F Ikuta
January 2014,
Meditsina truda i promyshlennaia ekologiia,
