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We examined levels of free triiodothyronine (fT3) and free thyroxine (fT4) in serum from a group of 32 patients with unipolar major depression and 46 normal control subjects using the Amerlex (Amersham, Arlington Heights, IL) RIA procedures for these hormones. Free T3 levels were significantly lower (p less than 0.004) in the depressed patients as a group (5.02 +/- 1.01 pmol/L, mean +/- SD) than in the normal control subjects (5.74 +/- 1.23 pmol/L). Free T3 levels were lower (p less than 0.01) in depressed men (5.25 +/- 1.43 pmol/L) when compared with male control subjects (6.46 +/- 1.01 pmol/L). Depressed women (4.78 +/- 0.60 pmol/L) also had lower T3 levels than did the female control subjects (5.09 +/- 1.06 pmol/L), but the difference was not statistically significant. Lower fT3 levels were also observed in melancholic depressed patients when compared with nonmelancholic depressed patients or when compared with normal control subjects. No differences in fT4 were observed between groups in this study.
P J Orsulak, and
G Crowley, and
M A Schlesser, and
D Giles, and
C Fairchild, and
A J Rush
January 1987,
Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas,
P J Orsulak, and
G Crowley, and
M A Schlesser, and
D Giles, and
C Fairchild, and
A J Rush
November 1979,
Metabolism: clinical and experimental,
P J Orsulak, and
G Crowley, and
M A Schlesser, and
D Giles, and
C Fairchild, and
A J Rush
January 1980,
Taiwan yi xue hui za zhi. Journal of the Formosan Medical Association,
P J Orsulak, and
G Crowley, and
M A Schlesser, and
D Giles, and
C Fairchild, and
A J Rush
May 1970,
The Journal of clinical investigation,
P J Orsulak, and
G Crowley, and
M A Schlesser, and
D Giles, and
C Fairchild, and
A J Rush
May 1974,
Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme,
P J Orsulak, and
G Crowley, and
M A Schlesser, and
D Giles, and
C Fairchild, and
A J Rush
October 2001,
Clinical chemistry and laboratory medicine,
P J Orsulak, and
G Crowley, and
M A Schlesser, and
D Giles, and
C Fairchild, and
A J Rush
January 1989,
Wiadomosci lekarskie (Warsaw, Poland : 1960),
P J Orsulak, and
G Crowley, and
M A Schlesser, and
D Giles, and
C Fairchild, and
A J Rush
December 1972,
Mayo Clinic proceedings,
P J Orsulak, and
G Crowley, and
M A Schlesser, and
D Giles, and
C Fairchild, and
A J Rush
July 1979,
Danish medical bulletin,
P J Orsulak, and
G Crowley, and
M A Schlesser, and
D Giles, and
C Fairchild, and
A J Rush
November 1976,
The Indian journal of medical research,
