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Patients with type B insulin resistance and acanthosis nigricans have autoantibodies to their insulin receptors and usually have signs and symptoms of other autoimmune diseases. The first case demonstrating that hyperalimentation markedly disturbs blood glucose control in type B insulin-resistant patients is described. Neither prednisone, insulin (up to 240 units per hour), nor tolbutamide appeared to help this patient's metabolic control. After the addition of cyclophosphamide for one week, the anti-insulin receptor autoantibody titer dropped from greater than 1:1,000 to 1:1. Six months later, the patient had a complete remission, which is rare, with only three other reported remissions in these patients with type B insulin resistance.
D L Vesely, and
M J Coleman, and
P O Kohler, and
R M Jordan, and
S Stanley
February 1988,
The American journal of medicine,
D L Vesely, and
M J Coleman, and
P O Kohler, and
R M Jordan, and
S Stanley
March 1979,
The New England journal of medicine,
D L Vesely, and
M J Coleman, and
P O Kohler, and
R M Jordan, and
S Stanley
February 2011,
Diabetes & metabolism journal,
D L Vesely, and
M J Coleman, and
P O Kohler, and
R M Jordan, and
S Stanley
January 1979,
Diabetes care,
D L Vesely, and
M J Coleman, and
P O Kohler, and
R M Jordan, and
S Stanley
April 1982,
Science (New York, N.Y.),
D L Vesely, and
M J Coleman, and
P O Kohler, and
R M Jordan, and
S Stanley
January 2000,
Acta diabetologica,
D L Vesely, and
M J Coleman, and
P O Kohler, and
R M Jordan, and
S Stanley
January 2022,
International journal of biochemistry and molecular biology,
D L Vesely, and
M J Coleman, and
P O Kohler, and
R M Jordan, and
S Stanley
January 1982,
Hormone research,
D L Vesely, and
M J Coleman, and
P O Kohler, and
R M Jordan, and
S Stanley
October 2005,
Medizinische Monatsschrift fur Pharmazeuten,
D L Vesely, and
M J Coleman, and
P O Kohler, and
R M Jordan, and
S Stanley
December 1982,
Annals of internal medicine,
