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Orthostatic hypotension in a patient with Shy-Drager syndrome was treated for 6 months with oral DL-threo-3,4-dihydroxyphenylserine (DL-threo-DOPS). Adrenergic function was evaluated before and during treatment by measurements of changes in blood pressure and plasma norepinephrine on head-up tilting and by the response of blood pressure to the Valsalva maneuver and infused norepinephrine. After the patient received DL-threo-DOPS, the fall in his mean arterial blood pressure on head-up tilting was reduced and he had no syncope when standing. When peripheral decarboxylase inhibitor was combined with DL-threo-DOPS, the same beneficial effect on orthostatic hypotension was observed.
S Sakoda, and
T Suzuki, and
S Higa, and
M Ueji, and
S Kishimoto, and
M Matsumoto, and
S Yoneda
March 1987,
Rinsho shinkeigaku = Clinical neurology,
S Sakoda, and
T Suzuki, and
S Higa, and
M Ueji, and
S Kishimoto, and
M Matsumoto, and
S Yoneda
September 1984,
Clinical pharmacology and therapeutics,
S Sakoda, and
T Suzuki, and
S Higa, and
M Ueji, and
S Kishimoto, and
M Matsumoto, and
S Yoneda
December 1999,
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S Sakoda, and
T Suzuki, and
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July 1988,
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S Sakoda, and
T Suzuki, and
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M Ueji, and
S Kishimoto, and
M Matsumoto, and
S Yoneda
December 1996,
Neurology,
S Sakoda, and
T Suzuki, and
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M Ueji, and
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M Matsumoto, and
S Yoneda
February 1967,
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S Sakoda, and
T Suzuki, and
S Higa, and
M Ueji, and
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May 1978,
Lancet (London, England),
S Sakoda, and
T Suzuki, and
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M Ueji, and
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S Yoneda
December 2004,
Journal of neurology, neurosurgery, and psychiatry,
S Sakoda, and
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M Matsumoto, and
S Yoneda
January 1983,
Revista de medicina interna, neurologie, psihiatrie, neurochirurgie, dermato-venerologie. Neurologie, psihiatrie, neurochirurgie,
S Sakoda, and
T Suzuki, and
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M Ueji, and
S Kishimoto, and
M Matsumoto, and
S Yoneda
June 1975,
South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde,
