[Late acoustically evoked potentials--effect of age, sex and different study conditions]. 1985

U Hegerl, and S Klotz, and G Ulrich

54 healthy volunteers (25-82 years) were studied in an "auditory oddball" event-related potential paradigm. The tones (80%, 800 Hz; 20%, 1,600 Hz) were presented via two earphones in an randomized form. The rare tones were counted by the volunteers. Each volunteer was tested with the conditions, "eyes open" and "eyes closed". We found: An increase of the P3-latency of 0.92 ms/year (280 ms in the age of 20 years), and a decrease of P3-amplitude of 0.14 microV/year (17.2 microV in the age of 20 years). In contrast to other studies, the amplitude of the P2-wave (12.8 ms in the age of 20 years) and the latency of the P2-wave (160 ms in the age of 20 years) was not influenced by age. Females showed greater amplitudes of the P2- and P3-components. Females showed a clearly smaller increase on P3-latency with age (0.25 ms/year, starting with 296 ms in the age of 20 years) than males (1.3 ms/year, starting with 272 ms in the age of 20 years). The condition "eyes open" or "eyes closed" did not influence the late auditory evoked potentials. The results were interpreted by taking into account the great sensitivity of the late evoked potentials for changes of the state, which can be defined as well on the neurophysiological level as on the behavioural level.

UI MeSH Term Description Entries
D008297 Male Males
D008875 Middle Aged An adult aged 45 - 64 years. Middle Age
D011930 Reaction Time The time from the onset of a stimulus until a response is observed. Response Latency,Response Speed,Response Time,Latency, Response,Reaction Times,Response Latencies,Response Times,Speed, Response,Speeds, Response
D005072 Evoked Potentials, Auditory The electric response evoked in the CEREBRAL CORTEX by ACOUSTIC STIMULATION or stimulation of the AUDITORY PATHWAYS. Auditory Evoked Potentials,Auditory Evoked Response,Auditory Evoked Potential,Auditory Evoked Responses,Evoked Potential, Auditory,Evoked Response, Auditory,Evoked Responses, Auditory,Potentials, Auditory Evoked
D005260 Female Females
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000161 Acoustic Stimulation Use of sound to elicit a response in the nervous system. Auditory Stimulation,Stimulation, Acoustic,Stimulation, Auditory
D000328 Adult A person having attained full growth or maturity. Adults are of 19 through 44 years of age. For a person between 19 and 24 years of age, YOUNG ADULT is available. Adults
D000367 Age Factors Age as a constituent element or influence contributing to the production of a result. It may be applicable to the cause or the effect of a circumstance. It is used with human or animal concepts but should be differentiated from AGING, a physiological process, and TIME FACTORS which refers only to the passage of time. Age Reporting,Age Factor,Factor, Age,Factors, Age
D000368 Aged A person 65 years of age or older. For a person older than 79 years, AGED, 80 AND OVER is available. Elderly

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