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The erythrocytes from the vitamin E-deficient rats showed no changes in comparison with the erythrocytes from the vitamin E-supplemented rats in lipid peroxides, membrane fluidity, lipid composition, and activities of defensive enzymes against the lipid peroxide formation. Once erythrocytes from vitamin E-deficient rats were exposed to H2O2, the erythrocyte membrane fluidity was significantly reduced, which was presumed to be accompanied by an increase in the hemolysis and lipid peroxide formation. Large decreases in arachidonic acid and phospholipid were also observed. These findings suggest that the reduced membrane fluidity is due to the loss of phospholipid from the erythrocytes, and raises the possibility that the reduced fluidity might contribute to the peroxidative hemolysis of the vitamin E-deficient rat erythrocytes.
K Kameda, and
M Imai, and
M Senjo
February 1982,
Journal of lipid research,
K Kameda, and
M Imai, and
M Senjo
November 1958,
The Journal of biological chemistry,
K Kameda, and
M Imai, and
M Senjo
January 1978,
Acta vitaminologica et enzymologica,
K Kameda, and
M Imai, and
M Senjo
February 1960,
The Journal of nutrition,
K Kameda, and
M Imai, and
M Senjo
January 1982,
Annals of the New York Academy of Sciences,
K Kameda, and
M Imai, and
M Senjo
December 1973,
The Proceedings of the Nutrition Society,
K Kameda, and
M Imai, and
M Senjo
January 1972,
Bollettino dell'Istituto sieroterapico milanese,
K Kameda, and
M Imai, and
M Senjo
January 1972,
Vitamins and hormones,
K Kameda, and
M Imai, and
M Senjo
January 1984,
International journal for vitamin and nutrition research. Internationale Zeitschrift fur Vitamin- und Ernahrungsforschung. Journal international de vitaminologie et de nutrition,
K Kameda, and
M Imai, and
M Senjo
April 1947,
Archives of pathology,
