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Antianginal therapy with long-acting nitrates, beta-blockers, and combinations there of were administered depending on the baseline cardiovascular function, as assessed by spiroergometry, in 300 patients with chronic coronary heart disease. Three degrees of the hypokinetic type corresponding to the degrees of myocardial failure were identified on the basis of adaptability patterns and the disturbance of correlations between the increment in oxygen consumption, heart rate, cardiac output, and the output of work done. It is shown that cardiovascular status should be taken into account in selecting the type of antianginal therapy for chronic coronary patients.
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