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Antithrombin III (AT III) levels have been reported to be low, normal, and high in diabetes mellitus. Furthermore, a discrepancy between AT III activity and antigen concentration was reported. We have evaluated the behaviour of AT III activity and antigen level both in type 1 and type 2 diabetes, either in uncontrolled or in well controlled patients. AT III activity and antigen levels showed values similar to normal. No difference was seen between type 1 and type 2 diabetes. Similar results were observed in the group of well controlled diabetic patients. AT III activity and antigen did not correlate with blood glucose and glycosylated haemoglobin (HbA1). No difference was observed between AT III activity and antigen levels in any group. Therefore the hypercoagulable state found in diabetes mellitus does not depend on AT III modifications. A discrepancy between AT III activity and antigen was not confirmed. A dysantithrombinaemia, explained on the basis of an inactivation of protein glycosylation in diabetes mellitus has not been confirmed.
G M Patrassi, and
R Picchinenna, and
R Vettor, and
G Cappellato, and
D Coccarielli, and
A Girolami
October 1987,
Kinderarztliche Praxis,
G M Patrassi, and
R Picchinenna, and
R Vettor, and
G Cappellato, and
D Coccarielli, and
A Girolami
January 1992,
Nouvelle revue francaise d'hematologie,
G M Patrassi, and
R Picchinenna, and
R Vettor, and
G Cappellato, and
D Coccarielli, and
A Girolami
January 1992,
Journal of diabetes and its complications,
G M Patrassi, and
R Picchinenna, and
R Vettor, and
G Cappellato, and
D Coccarielli, and
A Girolami
January 1985,
Scandinavian journal of clinical and laboratory investigation. Supplementum,
G M Patrassi, and
R Picchinenna, and
R Vettor, and
G Cappellato, and
D Coccarielli, and
A Girolami
November 1978,
Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme,
G M Patrassi, and
R Picchinenna, and
R Vettor, and
G Cappellato, and
D Coccarielli, and
A Girolami
October 1980,
Nihon Ketsueki Gakkai zasshi : journal of Japan Haematological Society,
G M Patrassi, and
R Picchinenna, and
R Vettor, and
G Cappellato, and
D Coccarielli, and
A Girolami
October 1976,
Scandinavian journal of haematology,
G M Patrassi, and
R Picchinenna, and
R Vettor, and
G Cappellato, and
D Coccarielli, and
A Girolami
January 1983,
Medecine interne,
G M Patrassi, and
R Picchinenna, and
R Vettor, and
G Cappellato, and
D Coccarielli, and
A Girolami
July 1987,
Thrombosis research,
G M Patrassi, and
R Picchinenna, and
R Vettor, and
G Cappellato, and
D Coccarielli, and
A Girolami
January 1984,
Zeitschrift fur Geburtshilfe und Perinatologie,
