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Biopsies from 28 patients with urinary bladder carcinoma were investigated by flow cytometry and morphometry. Histopathological grading on 1.5 microns thick glycol methacrylate sections was also performed. Nuclear profile areas, nuclear volume densities and mitotic indices were usually larger in the higher grades of malignancy. All grade I tumours were diploid and all grade III tumours were aneuploid. Out of 13 grade II tumours 8 were diploid and 5 aneuploid. In these latter five cases nuclear profile areas were at the high end of the spectrum. The data show that flow cytometry and morphometry could be a valuable tool in the diagnosis of urinary bladder carcinoma. Our data also suggest that a subdivision of the grade II tumours might be possible and meaningful in the assessment of prognosis.
K Helander, and
B Kirkhus, and
O H Iversen, and
S L Johansson, and
S Nilsson, and
S Vaage, and
H Fjordvang
February 1963,
Hinyokika kiyo. Acta urologica Japonica,
K Helander, and
B Kirkhus, and
O H Iversen, and
S L Johansson, and
S Nilsson, and
S Vaage, and
H Fjordvang
January 1973,
Scandinavian journal of urology and nephrology,
K Helander, and
B Kirkhus, and
O H Iversen, and
S L Johansson, and
S Nilsson, and
S Vaage, and
H Fjordvang
August 1992,
Zhongguo yi xue ke xue yuan xue bao. Acta Academiae Medicinae Sinicae,
K Helander, and
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O H Iversen, and
S L Johansson, and
S Nilsson, and
S Vaage, and
H Fjordvang
January 1978,
European urology,
K Helander, and
B Kirkhus, and
O H Iversen, and
S L Johansson, and
S Nilsson, and
S Vaage, and
H Fjordvang
March 1989,
American journal of clinical pathology,
K Helander, and
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H Fjordvang
January 1991,
Analytical cellular pathology : the journal of the European Society for Analytical Cellular Pathology,
K Helander, and
B Kirkhus, and
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S L Johansson, and
S Nilsson, and
S Vaage, and
H Fjordvang
November 1989,
Pathology, research and practice,
K Helander, and
B Kirkhus, and
O H Iversen, and
S L Johansson, and
S Nilsson, and
S Vaage, and
H Fjordvang
December 1962,
Nihon Hinyokika Gakkai zasshi. The japanese journal of urology,
K Helander, and
B Kirkhus, and
O H Iversen, and
S L Johansson, and
S Nilsson, and
S Vaage, and
H Fjordvang
April 1994,
Zentralblatt fur Veterinarmedizin. Reihe B. Journal of veterinary medicine. Series B,
K Helander, and
B Kirkhus, and
O H Iversen, and
S L Johansson, and
S Nilsson, and
S Vaage, and
H Fjordvang
January 1984,
Der Urologe. Ausg. A,
