BIOMAT Database Logo BIOMAT Database Logo

Antimicrobial cream susceptibility testing. 1985

J M Conly, and S Byrne, and J McLeod, and S Hoban, and G Robertson, and A R Ronald

Utilizing a recently described rapid needle extrusion method for determining the sensitivities of burn wound isolates, we have compiled data on the resistance patterns of over 250 isolates from our burn unit. Major isolate groups were Staphylococcus aureus, Pseudomonas aeruginosa, various Enterobacteriaceae and Enterococci. Excellent correlation was exhibited between the inhibitory zone sizes and the minimal inhibitory concentration for 120 organisms tested. Utilizing the needle extrusion sensitivities to facilitate the selection of the burn creams, a significant reduction in the microbiologic flora of the burn wound was noted. The utilization of this technique in the selection of burn creams deserves controlled trials to assess whether changes in topical therapy might alter clinical outcome.

UI MeSH Term Description Entries
D008826 Microbial Sensitivity Tests Any tests that demonstrate the relative efficacy of different chemotherapeutic agents against specific microorganisms (i.e., bacteria, fungi, viruses). Bacterial Sensitivity Tests,Drug Sensitivity Assay, Microbial,Minimum Inhibitory Concentration,Antibacterial Susceptibility Breakpoint Determination,Antibiogram,Antimicrobial Susceptibility Breakpoint Determination,Bacterial Sensitivity Test,Breakpoint Determination, Antibacterial Susceptibility,Breakpoint Determination, Antimicrobial Susceptibility,Fungal Drug Sensitivity Tests,Fungus Drug Sensitivity Tests,Sensitivity Test, Bacterial,Sensitivity Tests, Bacterial,Test, Bacterial Sensitivity,Tests, Bacterial Sensitivity,Viral Drug Sensitivity Tests,Virus Drug Sensitivity Tests,Antibiograms,Concentration, Minimum Inhibitory,Concentrations, Minimum Inhibitory,Inhibitory Concentration, Minimum,Inhibitory Concentrations, Minimum,Microbial Sensitivity Test,Minimum Inhibitory Concentrations,Sensitivity Test, Microbial,Sensitivity Tests, Microbial,Test, Microbial Sensitivity,Tests, Microbial Sensitivity
D009583 Nitrofurazone A topical anti-infective agent effective against gram-negative and gram-positive bacteria. It is used for superficial WOUNDS AND INJURIES and skin infections. Nitrofurazone has also been administered orally in the treatment of TRYPANOSOMIASIS. Nitrofural,Furacilin,Furacillin,Furacin,Nitrofurazone, Calcium (2:1) Salt
D009824 Ointments Semisolid preparations used topically for protective emollient effects or as a vehicle for local administration of medications. Ointment bases are various mixtures of fats, waxes, animal and plant oils and solid and liquid hydrocarbons. Ointment,Paste,Pastes,Salve,Unguent,Salves,Skin Ointment,Unguents,Ointment, Skin
D011550 Pseudomonas aeruginosa A species of gram-negative, aerobic, rod-shaped bacteria commonly isolated from clinical specimens (wound, burn, and urinary tract infections). It is also found widely distributed in soil and water. P. aeruginosa is a major agent of nosocomial infection. Bacillus aeruginosus,Bacillus pyocyaneus,Bacterium aeruginosum,Bacterium pyocyaneum,Micrococcus pyocyaneus,Pseudomonas polycolor,Pseudomonas pyocyanea
D002056 Burns Injuries to tissues caused by contact with heat, steam, chemicals (BURNS, CHEMICAL), electricity (BURNS, ELECTRIC), or the like. Burn
D004755 Enterobacteriaceae A family of gram-negative, facultatively anaerobic, rod-shaped bacteria that do not form endospores. Its organisms are distributed worldwide with some being saprophytes and others being plant and animal parasites. Many species are of considerable economic importance due to their pathogenic effects on agriculture and livestock. Coliform Bacilli,Enterobacteria,Ewingella,Leclercia,Paracolobactrum,Sodalis
D004926 Escherichia coli A species of gram-negative, facultatively anaerobic, rod-shaped bacteria (GRAM-NEGATIVE FACULTATIVELY ANAEROBIC RODS) commonly found in the lower part of the intestine of warm-blooded animals. It is usually nonpathogenic, but some strains are known to produce DIARRHEA and pyogenic infections. Pathogenic strains (virotypes) are classified by their specific pathogenic mechanisms such as toxins (ENTEROTOXIGENIC ESCHERICHIA COLI), etc. Alkalescens-Dispar Group,Bacillus coli,Bacterium coli,Bacterium coli commune,Diffusely Adherent Escherichia coli,E coli,EAggEC,Enteroaggregative Escherichia coli,Enterococcus coli,Diffusely Adherent E. coli,Enteroaggregative E. coli,Enteroinvasive E. coli,Enteroinvasive Escherichia coli
D005839 Gentamicins A complex of closely related aminoglycosides obtained from MICROMONOSPORA purpurea and related species. They are broad-spectrum antibiotics, but may cause ear and kidney damage. They act to inhibit PROTEIN BIOSYNTHESIS. Gentamicin Sulfate (USP),Gentamycin,G-Myticin,Garamycin,Gentacycol,Gentamicin,Gentamicin Sulfate,Gentamycins,Gentavet,Genticin,G Myticin,GMyticin,Sulfate, Gentamicin
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000287 Administration, Topical The application of drug preparations to the surfaces of the body, especially the skin (ADMINISTRATION, CUTANEOUS) or mucous membranes. This method of treatment is used to avoid systemic side effects when high doses are required at a localized area or as an alternative systemic administration route, to avoid hepatic processing for example. Drug Administration, Topical,Administration, Topical Drug,Topical Administration,Topical Drug Administration,Administrations, Topical,Administrations, Topical Drug,Drug Administrations, Topical,Topical Administrations,Topical Drug Administrations

Related Publications

J M Conly, and S Byrne, and J McLeod, and S Hoban, and G Robertson, and A R Ronald
Topical antimicrobial cream sensitivity testing.
December 1980, Surgery, gynecology & obstetrics,
J M Conly, and S Byrne, and J McLeod, and S Hoban, and G Robertson, and A R Ronald
Antimicrobial susceptibility testing.
June 1989, Clinics in laboratory medicine,
J M Conly, and S Byrne, and J McLeod, and S Hoban, and G Robertson, and A R Ronald
[Antimicrobial susceptibility testing].
February 1994, Nihon rinsho. Japanese journal of clinical medicine,
J M Conly, and S Byrne, and J McLeod, and S Hoban, and G Robertson, and A R Ronald
Antimicrobial susceptibility testing.
May 1976, Human pathology,
J M Conly, and S Byrne, and J McLeod, and S Hoban, and G Robertson, and A R Ronald
European Committee on Antimicrobial Susceptibility Testing (EUCAST) Technical Notes on antimicrobial susceptibility testing.
June 2006, Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases,
J M Conly, and S Byrne, and J McLeod, and S Hoban, and G Robertson, and A R Ronald
Antimicrobial susceptibility testing and antimicrobial drug dosage.
August 1985, Journal of the American Veterinary Medical Association,
J M Conly, and S Byrne, and J McLeod, and S Hoban, and G Robertson, and A R Ronald
Antimicrobial susceptibility testing in Sweden. III. Methodology for susceptibility testing.
January 1997, Scandinavian journal of infectious diseases. Supplementum,
J M Conly, and S Byrne, and J McLeod, and S Hoban, and G Robertson, and A R Ronald
Updating antimicrobial susceptibility testing: introduction.
January 2012, Clinical laboratory science : journal of the American Society for Medical Technology,
J M Conly, and S Byrne, and J McLeod, and S Hoban, and G Robertson, and A R Ronald
Updating antimicrobial susceptibility testing: methods.
January 2012, Clinical laboratory science : journal of the American Society for Medical Technology,
J M Conly, and S Byrne, and J McLeod, and S Hoban, and G Robertson, and A R Ronald
Next-generation antimicrobial susceptibility testing.
July 2013, Journal of clinical microbiology,
Copied contents to your clipboard!