[Nuclear magnetic resonance study of the interaction of zinc with thymulin]. 1985

J P Laussac, and R Haran, and M Dardenne, and P Lefrancier, and J F Bach

Interaction of Zn2+ with thymulin was investigated by 1H NMR spectroscopy. In DMSO-d6 solution, Zn2+ forms a complex with a nonapeptide involving the C-terminal carboxylate and the hydroxyl groups of the two serine residues in position 4 and 8, in a tetrahedral structure.

UI MeSH Term Description Entries
D009682 Magnetic Resonance Spectroscopy Spectroscopic method of measuring the magnetic moment of elementary particles such as atomic nuclei, protons or electrons. It is employed in clinical applications such as NMR Tomography (MAGNETIC RESONANCE IMAGING). In Vivo NMR Spectroscopy,MR Spectroscopy,Magnetic Resonance,NMR Spectroscopy,NMR Spectroscopy, In Vivo,Nuclear Magnetic Resonance,Spectroscopy, Magnetic Resonance,Spectroscopy, NMR,Spectroscopy, Nuclear Magnetic Resonance,Magnetic Resonance Spectroscopies,Magnetic Resonance, Nuclear,NMR Spectroscopies,Resonance Spectroscopy, Magnetic,Resonance, Magnetic,Resonance, Nuclear Magnetic,Spectroscopies, NMR,Spectroscopy, MR
D000595 Amino Acid Sequence The order of amino acids as they occur in a polypeptide chain. This is referred to as the primary structure of proteins. It is of fundamental importance in determining PROTEIN CONFORMATION. Protein Structure, Primary,Amino Acid Sequences,Sequence, Amino Acid,Sequences, Amino Acid,Primary Protein Structure,Primary Protein Structures,Protein Structures, Primary,Structure, Primary Protein,Structures, Primary Protein
D013935 Thymic Factor, Circulating A thymus-dependent nonapeptide found in normal blood. Stimulates the formation of E rosettes and is believed to be involved in T-cell differentiation. Facteur Thymique Serique,Serum Thymic Factor,Circulating Factor, Thymic,Factor, Thymic Circulating,Nonathymulin,Thymic Serum Factor,Thymulin,Thymuline,Circulating Thymic Factor,Factor, Circulating Thymic,Factor, Serum Thymic,Factor, Thymic Serum,Serique, Facteur Thymique,Serum Factor, Thymic,Thymic Circulating Factor,Thymic Factor, Serum,Thymique Serique, Facteur
D013951 Thymus Hormones Humoral factors secreted by the thymus gland. They participate in the development of the lymphoid system and the maturation of the cellular immune response. Thymic Hormones,Hormones, Thymic,Hormones, Thymus
D015032 Zinc A metallic element of atomic number 30 and atomic weight 65.38. It is a necessary trace element in the diet, forming an essential part of many enzymes, and playing an important role in protein synthesis and in cell division. Zinc deficiency is associated with ANEMIA, short stature, HYPOGONADISM, impaired WOUND HEALING, and geophagia. It is known by the symbol Zn.

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