Biomaterial Database

The inhibition of lysosomal phospholipase A from rabbit lung by ambroxol and its consequences for pulmonary surfactant. 1985

M F Heath, and W Jacobson

UI	MeSH Term	Description	Entries
D008168	Lung	Either of the pair of organs occupying the cavity of the thorax that effect the aeration of the blood.	Lungs
D008247	Lysosomes	A class of morphologically heterogeneous cytoplasmic particles in animal and plant tissues characterized by their content of hydrolytic enzymes and the structure-linked latency of these enzymes. The intracellular functions of lysosomes depend on their lytic potential. The single unit membrane of the lysosome acts as a barrier between the enzymes enclosed in the lysosome and the external substrate. The activity of the enzymes contained in lysosomes is limited or nil unless the vesicle in which they are enclosed is ruptured or undergoes MEMBRANE FUSION. (From Rieger et al., Glossary of Genetics: Classical and Molecular, 5th ed).	Autolysosome,Autolysosomes,Lysosome
D010740	Phospholipases	A class of enzymes that catalyze the hydrolysis of phosphoglycerides or glycerophosphatidates. EC 3.1.-.	Lecithinases,Lecithinase,Phospholipase
D010741	Phospholipases A	Phospholipases that hydrolyze one of the acyl groups of phosphoglycerides or glycerophosphatidates.
D011817	Rabbits	A burrowing plant-eating mammal with hind limbs that are longer than its fore limbs. It belongs to the family Leporidae of the order Lagomorpha, and in contrast to hares, possesses 22 instead of 24 pairs of chromosomes.	Belgian Hare,New Zealand Rabbit,New Zealand Rabbits,New Zealand White Rabbit,Rabbit,Rabbit, Domestic,Chinchilla Rabbits,NZW Rabbits,New Zealand White Rabbits,Oryctolagus cuniculus,Chinchilla Rabbit,Domestic Rabbit,Domestic Rabbits,Hare, Belgian,NZW Rabbit,Rabbit, Chinchilla,Rabbit, NZW,Rabbit, New Zealand,Rabbits, Chinchilla,Rabbits, Domestic,Rabbits, NZW,Rabbits, New Zealand,Zealand Rabbit, New,Zealand Rabbits, New,cuniculus, Oryctolagus
D001964	Bromhexine	A mucolytic agent used in the treatment of respiratory disorders associated with viscid or excessive mucus. (From Martindale, The Extra Pharmacopoeia, 30th ed, p744)	Aparsonin,Bisolvon,Bromhexin,Bromhexin BC,Bromhexin Berlin-Chemie,Bromhexin-ratiopharm,Bromhexine Hydrochloride,Bromhexine Monohydrochloride,Brotussol,Darolan,Dur-Elix,Famel Bromhexine,Flegamin,Flubron,Hustentabs-ratiopharm,Mucohexine,NA-274,Quentan,Tesacof,bromhexin von ct,BC, Bromhexin,Bromhexin Berlin Chemie,Bromhexin BerlinChemie,Bromhexin ratiopharm,Bromhexine, Famel,Bromhexinratiopharm,Dur Elix,DurElix,Hustentabs ratiopharm,Hustentabsratiopharm,Hydrochloride, Bromhexine,Monohydrochloride, Bromhexine,NA 274,NA274,ct, bromhexin von,von ct, bromhexin
D000551	Ambroxol	A metabolite of BROMHEXINE that stimulates mucociliary action and clears the air passages in the respiratory tract. It is usually administered as the hydrochloride.	Bromhexine Metabolite VIII,4-(((2-Amino-3,5-dibromophenyl)methyl)amino)cyclohexanol,AMBROPP,Abrohexal,Ambril,Ambro-Puren,Ambrobeta,Ambrofur,Ambrohexal,Ambrolitic,Ambrolös,Ambroten,Ambroxin,Ambroxocompren,Bisolvon AM,Bronchopront,Bronchowern,Broxol,Contac Husten-Trunk,Dinobroxol,Duramucal,Ebromin,Expeflen,Expit,Farmabroxol,Flavamed,Frenopect,Gelopol,Larylin Husten-Löser,Lasolvan,Mibrox,Motosol,Muco-Fips,Mucosolvan,Mucotablin,NA-872,Pect Hustenlöser,Pulmonal S,Pädiamuc,Ringelheimer Pulmonal,Sekretovit,Surbronc,Therapin Hustenlöser,stas-Hustenlöser,AM, Bisolvon,Ambro Puren,AmbroPuren,Contac Husten Trunk,Contac HustenTrunk,Hustenlöser, Pect,Hustenlöser, Therapin,Larylin Husten Löser,Larylin HustenLöser,Metabolite VIII, Bromhexine,Muco Fips,MucoFips,NA 872,NA872,Pulmonal, Ringelheimer,stas Hustenlöser,stasHustenlöser
D000818	Animals	Unicellular or multicellular, heterotrophic organisms, that have sensation and the power of voluntary movement. Under the older five kingdom paradigm, Animalia was one of the kingdoms. Under the modern three domain model, Animalia represents one of the many groups in the domain EUKARYOTA.	Animal,Metazoa,Animalia