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Of 207 patients with acute bacterial meningitis previously reported by Dodge and Swartz, seizures occurred in 56 (27%). Most seizures began on the first or second day, and most stopped within two days. Seizures occurred most often at the extremes of life. Age-adjusted seizure frequency was greater with Hemophilus influenzae meningitis than with Streptococcus pneumoniae or Neisseria meningitidis. When seizures complicated bacterial meningitis, age-corrected mortality increased from 24% to 38%. Though seizures after recovery were infrequent (2.7% of cases), recurrences were five times more frequent in patients who convulsed acutely than in those who did not. When focal seizures accompanied focal pathology (extracranial or intracranial), the seizures were usually not lateralized to the opposite side of the body. Of factors of potential importance in causation of seizures, fever was the most important risk factor regardless of patient age.
N P Rosman, and
D B Peterson, and
E M Kaye, and
T Colton
January 1992,
Antibiotics and chemotherapy,
N P Rosman, and
D B Peterson, and
E M Kaye, and
T Colton
September 1998,
The Journal of infection,
N P Rosman, and
D B Peterson, and
E M Kaye, and
T Colton
May 2008,
Neurology,
N P Rosman, and
D B Peterson, and
E M Kaye, and
T Colton
September 1999,
Infectious disease clinics of North America,
N P Rosman, and
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T Colton
January 1999,
Revista de neurologia,
N P Rosman, and
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T Colton
September 2004,
Pediatric neurology,
N P Rosman, and
D B Peterson, and
E M Kaye, and
T Colton
September 1992,
The New England journal of medicine,
N P Rosman, and
D B Peterson, and
E M Kaye, and
T Colton
April 1993,
Clinical microbiology reviews,
N P Rosman, and
D B Peterson, and
E M Kaye, and
T Colton
January 1993,
Annual review of medicine,
N P Rosman, and
D B Peterson, and
E M Kaye, and
T Colton
February 1967,
South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde,
