Biomaterial Database

Defective interfering viruses: modulators of infection. 1985

N J Dimmock

Department of Biological Sciences, University of Warwick, Coventry, UK.

Defective interfering viruses are powerful modulators of infection which can completely alter the manifestation of virus disease or convert the disease into a symptomless infection. Although their structural biochemistry has been widely studied, their biology is still poorly understood, probably because its complexity has been underestimated.

UI	MeSH Term	Description	Entries
D003673	Defective Viruses	Viruses which lack a complete genome so that they cannot completely replicate or cannot form a protein coat. Some are host-dependent defectives, meaning they can replicate only in cell systems which provide the particular genetic function which they lack. Others, called SATELLITE VIRUSES, are able to replicate only when their genetic defect is complemented by a helper virus.	Incomplete Viruses,Defective Hybrids,Defective Hybrid,Defective Virus,Hybrid, Defective,Hybrids, Defective,Incomplete Virus,Virus, Defective,Virus, Incomplete,Viruses, Defective,Viruses, Incomplete
D006801	Humans	Members of the species Homo sapiens.	Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000818	Animals	Unicellular or multicellular, heterotrophic organisms, that have sensation and the power of voluntary movement. Under the older five kingdom paradigm, Animalia was one of the kingdoms. Under the modern three domain model, Animalia represents one of the many groups in the domain EUKARYOTA.	Animal,Metazoa,Animalia
D014777	Virus Diseases	A general term for diseases caused by viruses.	Viral Diseases,Viral Infections,Virus Infections,Disease, Viral,Disease, Virus,Diseases, Viral,Diseases, Virus,Infection, Viral,Infection, Virus,Infections, Viral,Infections, Virus,Viral Disease,Viral Infection,Virus Disease,Virus Infection
D014780	Viruses	Minute infectious agents whose genomes are composed of DNA or RNA, but not both. They are characterized by a lack of independent metabolism and the inability to replicate outside living host cells.	Animal Viruses,Zoophaginae,Animal Virus,Virus,Virus, Animal,Viruses, Animal
D018406	Virus Physiological Phenomena	Biological properties, processes, and activities of VIRUSES, including the interactions with the cells they infect.	Viral Physiological Processes,Viral Physiology,Virus Physiological Processes,Physiology, Viral,Viral Physiological Concepts,Viral Physiological Phenomena,Viral Physiological Process,Virus Physiological Concepts,Virus Physiological Phenomenon,Virus Physiological Process,Virus Physiology,Concept, Viral Physiological,Concept, Virus Physiological,Concepts, Viral Physiological,Concepts, Virus Physiological,Phenomena, Viral Physiological,Phenomena, Virus Physiological,Phenomenon, Virus Physiological,Phenomenons, Virus Physiological,Physiological Process, Viral,Physiological Process, Virus,Physiological Processes, Viral,Physiological Processes, Virus,Physiology, Virus,Process, Viral Physiological,Process, Virus Physiological,Processes, Viral Physiological,Processes, Virus Physiological,Viral Physiological Concept,Virus Physiological Concept