Sinusoidal fetal heart rate pattern after administration of nalbuphine hydrochloride: a case report. 1986

S J Feinstein, and J G Lodeiro, and A M Vintzileos, and W A Campbell, and J T Montgomery, and D J Nochimson

Nalbuphine hydrochloride (Nubain) is a synthetic analgesic available for use during labor. It is known to possibly cause respiratory depression in the neonate, but to date there are no published reports of any intrapartum alterations of fetal heart rate. A case presentation is given of a persistent sinusoidal pattern appearing after Nubain administration.

UI MeSH Term Description Entries
D009019 Morphinans Compounds based on a partially saturated iminoethanophenanthrene, which can be described as ethylimino-bridged benzo-decahydronaphthalenes. They include some of the OPIOIDS found in PAPAVER that are used as ANALGESICS. Morphinan
D009266 Nalbuphine A narcotic used as a pain medication. It appears to be an agonist at KAPPA RECEPTORS and an antagonist or partial agonist at MU RECEPTORS. EN-2234A,Nalbuphine Hydrochloride,Nalbuphine Serb,Nubain,EN 2234A,EN2234A
D010500 Perinatology The branch of medicine dealing with the FETUS and NEWBORN during the perinatal period. The perinatal period begins with the twenty-eighth week of gestation and ends twenty-eight days after birth. Fetal Medicine,Maternal-Fetal Medicine,Materno-Fetal Medicine,Fetal Medicines,Maternal Fetal Medicine,Maternal-Fetal Medicines,Materno Fetal Medicine,Materno-Fetal Medicines,Medicine, Fetal,Medicine, Maternal-Fetal,Medicine, Materno-Fetal
D005318 Fetal Heart The heart of the fetus of any viviparous animal. It refers to the heart in the postembryonic period and is differentiated from the embryonic heart (HEART/embryology) only on the basis of time. Fetal Hearts,Heart, Fetal,Hearts, Fetal
D006207 Half-Life The time it takes for a substance (drug, radioactive nuclide, or other) to lose half of its pharmacologic, physiologic, or radiologic activity. Halflife,Half Life,Half-Lifes,Halflifes
D006339 Heart Rate The number of times the HEART VENTRICLES contract per unit of time, usually per minute. Cardiac Rate,Chronotropism, Cardiac,Heart Rate Control,Heartbeat,Pulse Rate,Cardiac Chronotropy,Cardiac Chronotropism,Cardiac Rates,Chronotropy, Cardiac,Control, Heart Rate,Heart Rates,Heartbeats,Pulse Rates,Rate Control, Heart,Rate, Cardiac,Rate, Heart,Rate, Pulse
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000328 Adult A person having attained full growth or maturity. Adults are of 19 through 44 years of age. For a person between 19 and 24 years of age, YOUNG ADULT is available. Adults

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