Biomaterial Database

Resting energy expenditure in moderate obesity. Predicting velocity of weight loss. 1986

K N Pavlou, and M A Hoefer, and G L Blackburn

The predicted resting metabolic rate (pRMR), as is estimated by the Harris-Benedict equation (HBE), was compared with the actual resting metabolic rate (mRMR), as assessed by indirect calorimetry, in 31 moderately obese (mean above ideal body weight = 44 +/- 2.8%) male subjects (mean age = 48 +/- 4.5 years; mean weight = 107.3 +/- 17.1 kg; mean% fat = 34 +/- 3.9). Measured resting metabolic rate (mRMR) (1,942 +/- 293 kcal/day) was found to be significantly (p less than 0.001) lower than pRMR (2,108 +/- 270 kcal/day), but significantly higher (p less than 0.001) than pRMR (1,636 +/- 133 kcal/day), if ideal body weight was used in the HBE formula. Individual variation of the mRMR and pRMR ranged from 65-105% and 95-155% of the expected normal population values, respectively. The findings suggest that if the reduced daily caloric needs observed are added to the metabolic suppression occurring during dietary restriction, it might explain why many obese individuals experience difficulties in maintaining predicted rates of weight loss. An equation was derived to predict RMR in moderately obese male patients.

UI	MeSH Term	Description	Entries
D008297	Male		Males
D008875	Middle Aged	An adult aged 45 - 64 years.	Middle Age
D009765	Obesity	A status with BODY WEIGHT that is grossly above the recommended standards, usually due to accumulation of excess FATS in the body. The standards may vary with age, sex, genetic or cultural background. In the BODY MASS INDEX, a BMI greater than 30.0 kg/m2 is considered obese, and a BMI greater than 40.0 kg/m2 is considered morbidly obese (MORBID OBESITY).
D001835	Body Weight	The mass or quantity of heaviness of an individual. It is expressed by units of pounds or kilograms.	Body Weights,Weight, Body,Weights, Body
D002149	Energy Intake	Total number of calories taken in daily whether ingested or by parenteral routes.	Caloric Intake,Calorie Intake,Intake, Calorie,Intake, Energy
D002151	Calorimetry	The measurement of the quantity of heat involved in various processes, such as chemical reactions, changes of state, and formations of solutions, or in the determination of the heat capacities of substances. The fundamental unit of measurement is the joule or the calorie (4.184 joules). (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)
D006801	Humans	Members of the species Homo sapiens.	Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000328	Adult	A person having attained full growth or maturity. Adults are of 19 through 44 years of age. For a person between 19 and 24 years of age, YOUNG ADULT is available.	Adults
D001481	Basal Metabolism	Metabolism (e.g., heat production) of an organism in an inactive, awake, fasting state. It may be determined directly by means of a calorimeter or indirectly by calculating the end products of oxidation within the organism or from the amount of oxygen utilized.	Metabolism, Basal,Basal Metabolic Rate,Metabolic Rate, Basal,Resting Metabolic Rate,Basal Metabolic Rates,Metabolic Rate, Resting,Rate, Basal Metabolic,Rate, Resting Metabolic,Resting Metabolic Rates
D013997	Time Factors	Elements of limited time intervals, contributing to particular results or situations.	Time Series,Factor, Time,Time Factor