Hypertensive crisis associated with nifedipine withdrawal. 1986

M Bursztyn, and K Tordjman, and E Grossman, and T Rosenthal

A 71-year-old hypertensive patient experienced a severe hypertensive crisis. His blood pressure was 300/200 mm Hg three days after nifedipine therapy was discontinued. He had been taking nifedipine together with methyldopa. During five months on the combined treatment, his blood pressure had not risen higher than 170/100 mm Hg. A severe hypertensive crisis following abrupt nifedipine withdrawal has not been previously reported, to our knowledge. We recommend that caution be used when abrupt cessation of nifedipine therapy is considered in the treatment of hypertension.

UI MeSH Term Description Entries
D006973 Hypertension Persistently high systemic arterial BLOOD PRESSURE. Based on multiple readings (BLOOD PRESSURE DETERMINATION), hypertension is currently defined as when SYSTOLIC PRESSURE is consistently greater than 140 mm Hg or when DIASTOLIC PRESSURE is consistently 90 mm Hg or more. Blood Pressure, High,Blood Pressures, High,High Blood Pressure,High Blood Pressures
D008297 Male Males
D009543 Nifedipine A potent vasodilator agent with calcium antagonistic action. It is a useful anti-anginal agent that also lowers blood pressure. Adalat,BAY-a-1040,Bay-1040,Cordipin,Cordipine,Corinfar,Fenigidin,Korinfar,Nifangin,Nifedipine Monohydrochloride,Nifedipine-GTIS,Procardia,Procardia XL,Vascard,BAY a 1040,BAYa1040,Bay 1040,Bay1040,Monohydrochloride, Nifedipine,Nifedipine GTIS
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000368 Aged A person 65 years of age or older. For a person older than 79 years, AGED, 80 AND OVER is available. Elderly

Related Publications

M Bursztyn, and K Tordjman, and E Grossman, and T Rosenthal
January 1981, Bollettino della Societa italiana di cardiologia,
M Bursztyn, and K Tordjman, and E Grossman, and T Rosenthal
December 1983, British journal of clinical pharmacology,
M Bursztyn, and K Tordjman, and E Grossman, and T Rosenthal
November 1984, Medicina clinica,
M Bursztyn, and K Tordjman, and E Grossman, and T Rosenthal
July 1985, Revista clinica espanola,
M Bursztyn, and K Tordjman, and E Grossman, and T Rosenthal
May 1987, Medicina clinica,
M Bursztyn, and K Tordjman, and E Grossman, and T Rosenthal
September 1988, Critical care medicine,
M Bursztyn, and K Tordjman, and E Grossman, and T Rosenthal
June 1987, The Journal of clinical psychiatry,
M Bursztyn, and K Tordjman, and E Grossman, and T Rosenthal
January 1983, Postgraduate medical journal,
M Bursztyn, and K Tordjman, and E Grossman, and T Rosenthal
January 1988, Intensive care medicine,
M Bursztyn, and K Tordjman, and E Grossman, and T Rosenthal
January 1989, Annals of emergency medicine,
Copied contents to your clipboard!