-transparent.png){kind=logo}
The acquired immunodeficiency syndrome (AIDS) is characterized by a severe idiopathic deficiency in T-cell mediated immunity. Homosexuals, intravenous drug abusers and Haitians are predominantly affected, predisposing them to opportunistic infections and neoplasms. In this study, the central nervous system (CNS) was examined at autopsy in 29 AIDS patients. Significant CNS complications occurred in 55%, mainly related to opportunistic infections similar to those seen in patients with other causes of immunosuppression. Progressive multifocal leukoencephalopathy (three cases), cytomegalovirus (CMV) encephalitis (five cases), cryptococcal meningitis (four cases), Mycobacterium avium-intracellulare (three cases), and toxoplasmosis (one case) were found. Widespread microglial nodules were observed in 20 patients, 80% of whom had CMV inclusions elsewhere at autopsy. Primary cerebral lymphoma (one case) and lymphomatoid granulomatosis (one case) were present. Subarachnoid (five cases) and intraparenchymal (three cases) hemorrhage was seen although these were not usually clinically significant. A single case of embolic arterial obstruction with cortical infarction was due to non-bacterial thrombotic endocarditis.
K Anders, and
K D Steinsapir, and
D J Iverson, and
B J Glasgow, and
L J Layfield, and
W J Brown, and
P A Cancilla, and
M A Verity, and
H V Vinters
January 1985,
Acta neuropathologica,
K Anders, and
K D Steinsapir, and
D J Iverson, and
B J Glasgow, and
L J Layfield, and
W J Brown, and
P A Cancilla, and
M A Verity, and
H V Vinters
January 1986,
Der Pathologe,
K Anders, and
K D Steinsapir, and
D J Iverson, and
B J Glasgow, and
L J Layfield, and
W J Brown, and
P A Cancilla, and
M A Verity, and
H V Vinters
January 1985,
Ultrastructural pathology,
K Anders, and
K D Steinsapir, and
D J Iverson, and
B J Glasgow, and
L J Layfield, and
W J Brown, and
P A Cancilla, and
M A Verity, and
H V Vinters
January 1991,
Annales de pathologie,
K Anders, and
K D Steinsapir, and
D J Iverson, and
B J Glasgow, and
L J Layfield, and
W J Brown, and
P A Cancilla, and
M A Verity, and
H V Vinters
December 1986,
The American journal of the medical sciences,
K Anders, and
K D Steinsapir, and
D J Iverson, and
B J Glasgow, and
L J Layfield, and
W J Brown, and
P A Cancilla, and
M A Verity, and
H V Vinters
May 1986,
Deutsche medizinische Wochenschrift (1946),
K Anders, and
K D Steinsapir, and
D J Iverson, and
B J Glasgow, and
L J Layfield, and
W J Brown, and
P A Cancilla, and
M A Verity, and
H V Vinters
March 1987,
Journal of the American Academy of Dermatology,
K Anders, and
K D Steinsapir, and
D J Iverson, and
B J Glasgow, and
L J Layfield, and
W J Brown, and
P A Cancilla, and
M A Verity, and
H V Vinters
April 1987,
Journal of the American Academy of Dermatology,
K Anders, and
K D Steinsapir, and
D J Iverson, and
B J Glasgow, and
L J Layfield, and
W J Brown, and
P A Cancilla, and
M A Verity, and
H V Vinters
February 1992,
Oral surgery, oral medicine, and oral pathology,
K Anders, and
K D Steinsapir, and
D J Iverson, and
B J Glasgow, and
L J Layfield, and
W J Brown, and
P A Cancilla, and
M A Verity, and
H V Vinters
September 1985,
Fortschritte der Medizin,
