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Fifty-three couples with longstanding infertility, the woman being potentially fertile and the man having poor-quality semen, were admitted to a therapeutic trial. A high intrauterine instillation of a washed motile fraction of spermatozoa from the subfertile man was performed in the woman on the day of ovulation. After 130 treatment cycles, 9 of the 53 women had conceived, all within 3 cycles. This simple and painless procedure can be considered an alternative treatment in oligoasthenoteratospermia.
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