BIOMAT Database Logo BIOMAT Database Logo

Device for rapid quantification of human carotid baroreceptor-cardiac reflex responses. 1986

J M Sprenkle, and D L Eckberg, and R L Goble, and J J Schelhorn, and H C Halliday

We designed, constructed, and evaluated a new device to characterize the human carotid baroreceptor-cardiac reflex response relation rapidly. We designed this system for study of reflex responses of astronauts before, during, and after space travel. The system comprises a new tightly sealing silicone rubber neck chamber, a stepping motor-driven electro-deposited nickel bellows pressure system, capable of delivering sequential R-wave-triggered neck chamber pressure changes between +40 and -65 mmHg, and a microprocessor-based electronics system for control of pressure steps and analysis and display of responses. This new system provokes classic sigmoid baroreceptor-cardiac reflex responses with threshold, linear, and saturation ranges in most human volunteers during one held expiration.

UI MeSH Term Description Entries
D009333 Neck The part of a human or animal body connecting the HEAD to the rest of the body. Necks
D011311 Pressoreceptors Receptors in the vascular system, particularly the aorta and carotid sinus, which are sensitive to stretch of the vessel walls. Baroreceptors,Receptors, Stretch, Arterial,Receptors, Stretch, Vascular,Stretch Receptors, Arterial,Stretch Receptors, Vascular,Arterial Stretch Receptor,Arterial Stretch Receptors,Baroreceptor,Pressoreceptor,Receptor, Arterial Stretch,Receptor, Vascular Stretch,Receptors, Arterial Stretch,Receptors, Vascular Stretch,Stretch Receptor, Arterial,Stretch Receptor, Vascular,Vascular Stretch Receptor,Vascular Stretch Receptors
D011312 Pressure A type of stress exerted uniformly in all directions. Its measure is the force exerted per unit area. (McGraw-Hill Dictionary of Scientific and Technical Terms, 6th ed) Pressures
D012018 Reflex An involuntary movement or exercise of function in a part, excited in response to a stimulus applied to the periphery and transmitted to the brain or spinal cord.
D001794 Blood Pressure PRESSURE of the BLOOD on the ARTERIES and other BLOOD VESSELS. Systolic Pressure,Diastolic Pressure,Pulse Pressure,Pressure, Blood,Pressure, Diastolic,Pressure, Pulse,Pressure, Systolic,Pressures, Systolic
D002346 Carotid Sinus The dilated portion of the common carotid artery at its bifurcation into external and internal carotids. It contains baroreceptors which, when stimulated, cause slowing of the heart, vasodilatation, and a fall in blood pressure. Sinus, Carotid
D005069 Evaluation Studies as Topic Works about studies that determine the effectiveness or value of processes, personnel, and equipment, or the material on conducting such studies. Critique,Evaluation Indexes,Evaluation Methodology,Evaluation Report,Evaluation Research,Methodology, Evaluation,Pre-Post Tests,Qualitative Evaluation,Quantitative Evaluation,Theoretical Effectiveness,Use-Effectiveness,Critiques,Effectiveness, Theoretical,Evaluation Methodologies,Evaluation Reports,Evaluation, Qualitative,Evaluation, Quantitative,Evaluations, Qualitative,Evaluations, Quantitative,Indexes, Evaluation,Methodologies, Evaluation,Pre Post Tests,Pre-Post Test,Qualitative Evaluations,Quantitative Evaluations,Report, Evaluation,Reports, Evaluation,Research, Evaluation,Test, Pre-Post,Tests, Pre-Post,Use Effectiveness
D006321 Heart The hollow, muscular organ that maintains the circulation of the blood. Hearts
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D001698 Biomedical Engineering Application of principles and practices of engineering science to biomedical research and health care. Clinical Engineering,Engineering, Clinical,Engineering, Biomedical

Related Publications

J M Sprenkle, and D L Eckberg, and R L Goble, and J J Schelhorn, and H C Halliday
Reproducibility of human vagal carotid baroreceptor-cardiac reflex responses.
July 1992, The American journal of physiology,
J M Sprenkle, and D L Eckberg, and R L Goble, and J J Schelhorn, and H C Halliday
Short-duration spaceflight impairs human carotid baroreceptor-cardiac reflex responses.
August 1992, Journal of applied physiology (Bethesda, Md. : 1985),
J M Sprenkle, and D L Eckberg, and R L Goble, and J J Schelhorn, and H C Halliday
Adaptation of the human carotid baroreceptor-cardiac reflex.
August 1977, The Journal of physiology,
J M Sprenkle, and D L Eckberg, and R L Goble, and J J Schelhorn, and H C Halliday
Nonlinearities of the human carotid baroreceptor-cardiac reflex.
August 1980, Circulation research,
J M Sprenkle, and D L Eckberg, and R L Goble, and J J Schelhorn, and H C Halliday
Continuous resetting of the human carotid baroreceptor-cardiac reflex.
April 1987, The American journal of physiology,
J M Sprenkle, and D L Eckberg, and R L Goble, and J J Schelhorn, and H C Halliday
Carotid baroreceptor cardiac-vagal reflex responses during 10 days of head-down tilt.
February 1990, The Physiologist,
J M Sprenkle, and D L Eckberg, and R L Goble, and J J Schelhorn, and H C Halliday
Rapid resetting of the carotid baroreceptor reflex in the cat.
December 1981, The American journal of physiology,
J M Sprenkle, and D L Eckberg, and R L Goble, and J J Schelhorn, and H C Halliday
Influence of ten-day head-down bedrest on human carotid baroreceptor-cardiac reflex function.
January 1992, Acta physiologica Scandinavica. Supplementum,
J M Sprenkle, and D L Eckberg, and R L Goble, and J J Schelhorn, and H C Halliday
Carotid sinus baroreceptor reflex control of respiration.
November 1982, Circulation research,
J M Sprenkle, and D L Eckberg, and R L Goble, and J J Schelhorn, and H C Halliday
Rapid resetting of carotid baroreceptor reflex by afferent input from skeletal muscle receptors.
December 1998, The American journal of physiology,
Copied contents to your clipboard!