-transparent.png){kind=logo}
Some biological characteristics of cancer cells and solid tumors are identifiable by the high resolution NMR relaxation behavior of their nonaqueous components. Chemical analysis and two-dimensional scalar correlated (COSY) NMR spectroscopy show these resonances arise from neutral lipid in the plasma membrane. Triglyceride is shown to be the main plasma membrane component giving rise to the NMR spectrum, while soluble nonmembrane components account for 90% of the remaining resonances in the spectrum of intact cells. The presence of triglyceride has been detected by chemical analysis in highly purified plasma membranes from two different cell lines. The COSY spectra of cancer cells are comparable with that obtained for the triglyceride-rich very low density human lipoprotein.
G L May, and
L C Wright, and
K T Holmes, and
P G Williams, and
I C Smith, and
P E Wright, and
R M Fox, and
C E Mountford
May 1987,
FEBS letters,
G L May, and
L C Wright, and
K T Holmes, and
P G Williams, and
I C Smith, and
P E Wright, and
R M Fox, and
C E Mountford
November 2018,
Journal of magnetic resonance (San Diego, Calif. : 1997),
G L May, and
L C Wright, and
K T Holmes, and
P G Williams, and
I C Smith, and
P E Wright, and
R M Fox, and
C E Mountford
March 1998,
FEBS letters,
G L May, and
L C Wright, and
K T Holmes, and
P G Williams, and
I C Smith, and
P E Wright, and
R M Fox, and
C E Mountford
May 2009,
Journal of the American Chemical Society,
G L May, and
L C Wright, and
K T Holmes, and
P G Williams, and
I C Smith, and
P E Wright, and
R M Fox, and
C E Mountford
January 1985,
Physiological chemistry and physics and medical NMR,
G L May, and
L C Wright, and
K T Holmes, and
P G Williams, and
I C Smith, and
P E Wright, and
R M Fox, and
C E Mountford
July 1974,
Biochemical and biophysical research communications,
G L May, and
L C Wright, and
K T Holmes, and
P G Williams, and
I C Smith, and
P E Wright, and
R M Fox, and
C E Mountford
March 1984,
Biochemical and biophysical research communications,
G L May, and
L C Wright, and
K T Holmes, and
P G Williams, and
I C Smith, and
P E Wright, and
R M Fox, and
C E Mountford
September 1988,
European journal of biochemistry,
G L May, and
L C Wright, and
K T Holmes, and
P G Williams, and
I C Smith, and
P E Wright, and
R M Fox, and
C E Mountford
July 1987,
FEBS letters,
G L May, and
L C Wright, and
K T Holmes, and
P G Williams, and
I C Smith, and
P E Wright, and
R M Fox, and
C E Mountford
September 1980,
Biochemical and biophysical research communications,
