Biomaterial Database

Sublobar atelectasis and regional pulmonary blood flow. 1979

S Enjeti, and J T O'Neill, and P B Terry, and H A Menkes, and R J Traystman

We studied the effects of sublobar atelectasis on regional blood flow in anesthetized paralyzed pigs. Following the washout of nitrogen from the lung with oxygen, a sublobar airway was obstructed and a peripheral segment of lung allowed to collapse. Blood flow to the atelectatic region fell from a control of 140.0 +/- 20.5 to 16.6 +/- 2.9 ml/(min . g). Basilar regions that became atelectatic spontaneously during the course of the studies had similar decreases in blood flow. Inflation of the surrounding lung by the application of positive end-expiratory pressure failed to increase blood flow and vascular conductance within the atelectatic regions. These results indicate that mechanical and hypoxic effects on vessels perfusing sublobar atelectatic regions limit the effects of interdependence from the surrounding lung. Furthermore, with inflation of the surrounding lung, increases in pulmonary shunting of blood are small.

UI	MeSH Term	Description	Entries
D008168	Lung	Either of the pair of organs occupying the cavity of the thorax that effect the aeration of the blood.	Lungs
D011175	Positive-Pressure Respiration	A method of mechanical ventilation in which pressure is maintained to increase the volume of gas remaining in the lungs at the end of expiration, thus reducing the shunting of blood through the lungs and improving gas exchange.	Positive End-Expiratory Pressure,Positive-Pressure Ventilation,End-Expiratory Pressure, Positive,End-Expiratory Pressures, Positive,Positive End Expiratory Pressure,Positive End-Expiratory Pressures,Positive Pressure Respiration,Positive Pressure Ventilation,Positive-Pressure Respirations,Positive-Pressure Ventilations,Pressure, Positive End-Expiratory,Pressures, Positive End-Expiratory,Respiration, Positive-Pressure,Respirations, Positive-Pressure,Ventilation, Positive-Pressure,Ventilations, Positive-Pressure
D012039	Regional Blood Flow	The flow of BLOOD through or around an organ or region of the body.	Blood Flow, Regional,Blood Flows, Regional,Flow, Regional Blood,Flows, Regional Blood,Regional Blood Flows
D000818	Animals	Unicellular or multicellular, heterotrophic organisms, that have sensation and the power of voluntary movement. Under the older five kingdom paradigm, Animalia was one of the kingdoms. Under the modern three domain model, Animalia represents one of the many groups in the domain EUKARYOTA.	Animal,Metazoa,Animalia
D001261	Pulmonary Atelectasis	Absence of air in the entire or part of a lung, such as an incompletely inflated neonate lung or a collapsed adult lung. Pulmonary atelectasis can be caused by airway obstruction, lung compression, fibrotic contraction, or other factors.	Atelectasis, Congestive,Lung Collapse,Atelectasis,Compression Atelectasis,Compression Pulmonary Atelectasis,Congestive Atelectasis,Congestive Pulmonary Atelectasis,Contraction Pulmonary Atelectasis,Postoperative Pulmonary Atelectasis,Resorption Atelectasis,Resorption Pulmonary Atelectasis,Atelectases,Atelectases, Compression,Atelectases, Compression Pulmonary,Atelectases, Congestive,Atelectases, Congestive Pulmonary,Atelectases, Contraction Pulmonary,Atelectases, Postoperative Pulmonary,Atelectases, Pulmonary,Atelectases, Resorption,Atelectases, Resorption Pulmonary,Atelectasis, Compression,Atelectasis, Compression Pulmonary,Atelectasis, Congestive Pulmonary,Atelectasis, Contraction Pulmonary,Atelectasis, Postoperative Pulmonary,Atelectasis, Pulmonary,Atelectasis, Resorption,Atelectasis, Resorption Pulmonary,Collapse, Lung,Compression Atelectases,Compression Pulmonary Atelectases,Congestive Atelectases,Congestive Pulmonary Atelectases,Contraction Pulmonary Atelectases,Postoperative Pulmonary Atelectases,Pulmonary Atelectases,Pulmonary Atelectases, Compression,Pulmonary Atelectases, Congestive,Pulmonary Atelectases, Contraction,Pulmonary Atelectases, Postoperative,Pulmonary Atelectases, Resorption,Pulmonary Atelectasis, Compression,Pulmonary Atelectasis, Congestive,Pulmonary Atelectasis, Contraction,Pulmonary Atelectasis, Postoperative,Pulmonary Atelectasis, Resorption,Resorption Atelectases,Resorption Pulmonary Atelectases
D013552	Swine	Any of various animals that constitute the family Suidae and comprise stout-bodied, short-legged omnivorous mammals with thick skin, usually covered with coarse bristles, a rather long mobile snout, and small tail. Included are the genera Babyrousa, Phacochoerus (wart hogs), and Sus, the latter containing the domestic pig (see SUS SCROFA).	Phacochoerus,Pigs,Suidae,Warthogs,Wart Hogs,Hog, Wart,Hogs, Wart,Wart Hog
D014655	Vascular Resistance	The force that opposes the flow of BLOOD through a vascular bed. It is equal to the difference in BLOOD PRESSURE across the vascular bed divided by the CARDIAC OUTPUT.	Peripheral Resistance,Total Peripheral Resistance,Pulmonary Vascular Resistance,Systemic Vascular Resistance,Peripheral Resistance, Total,Resistance, Peripheral,Resistance, Pulmonary Vascular,Resistance, Systemic Vascular,Resistance, Total Peripheral,Resistance, Vascular,Vascular Resistance, Pulmonary,Vascular Resistance, Systemic