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A comparative radiographic and histological study was carried out in 126 patients with malignant and benign breast lesions. Prior to biopsy an additional film- and xeromammogram, both at oblique projection, were taken of each patient. The X-ray film was Definix Medical (Kodak), processed 5.5 minutes. The xerograms were taken with 1.5 mm aluminium total filtration, and developed by negative mode. The X-ray equipment consisted of a Senograph (CGR). The image evaluation was carried out independently by seven observers of varying experience in mammography by means of ROC-analysis. There is no loss of diagnostic information content in negative mode xeromammography, on the contrary, it seems to be slightly superior to film mammography.
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