-transparent.png){kind=logo}
Eosinophilic leukemias are difficult to individualize amid the hypereosinophilic syndromes. Chromosomal abnormalities when present within the eosinophils are of critical value in the diagnosis of a malignancy. We report here the case of a 27-year-old woman who had been healthy, until recently when she suddenly developed hepatosplenomegaly and lymph node enlargement, and considerable eosinophilia in blood and bone marrow. The morphologically abnormal cells (large pseudo Pelger eosinocytes) predominated in the cytology. The establishment in these cells of a clonal chromosomal anomaly, t(10;11)(p14;q21), favored the malignancy and diagnosis of acute eosinophilic leukemia.
Related Publications
A Broustet, and
P Bernard, and
D Dachary, and
B David, and
G Marit, and
F Lacombe, and
A M Issanchou, and
J Reiffers
August 1982,
[Rinsho ketsueki] The Japanese journal of clinical hematology,
A Broustet, and
P Bernard, and
D Dachary, and
B David, and
G Marit, and
F Lacombe, and
A M Issanchou, and
J Reiffers
January 1982,
Nouvelle revue francaise d'hematologie,
A Broustet, and
P Bernard, and
D Dachary, and
B David, and
G Marit, and
F Lacombe, and
A M Issanchou, and
J Reiffers
June 1988,
Leukemia,
A Broustet, and
P Bernard, and
D Dachary, and
B David, and
G Marit, and
F Lacombe, and
A M Issanchou, and
J Reiffers
June 2005,
Cancer genetics and cytogenetics,
A Broustet, and
P Bernard, and
D Dachary, and
B David, and
G Marit, and
F Lacombe, and
A M Issanchou, and
J Reiffers
June 2009,
Indian pediatrics,
A Broustet, and
P Bernard, and
D Dachary, and
B David, and
G Marit, and
F Lacombe, and
A M Issanchou, and
J Reiffers
February 2005,
Leukemia & lymphoma,
A Broustet, and
P Bernard, and
D Dachary, and
B David, and
G Marit, and
F Lacombe, and
A M Issanchou, and
J Reiffers
December 1992,
International journal of hematology,
A Broustet, and
P Bernard, and
D Dachary, and
B David, and
G Marit, and
F Lacombe, and
A M Issanchou, and
J Reiffers
January 1992,
Leukemia research,
A Broustet, and
P Bernard, and
D Dachary, and
B David, and
G Marit, and
F Lacombe, and
A M Issanchou, and
J Reiffers
January 2014,
Acta haematologica,
A Broustet, and
P Bernard, and
D Dachary, and
B David, and
G Marit, and
F Lacombe, and
A M Issanchou, and
J Reiffers
June 1983,
Cancer genetics and cytogenetics,
