BIOMAT Database Logo BIOMAT Database Logo

Susceptibility of Candida species strains to five antifungal agents: comparison between agar dilution and disk diffusion tests. 1986

M Trancassini, and M C Ghezzi, and P Cipriani, and C Mancini, and M I Brenciaglia

The in vitro activity of five antifungal agents were compared against 180 Candida strains. The drugs were: two imidazoles (miconazole and ketoconazole), nystatin, 5-fluorocytosine and amphotericin B. Agar dilution and disk diffusion methods were used. Nystatin, miconazole and amphotericin B were the most active agents. 5-fluorocytosine had high activity except against C. albicans serotype B, of which a high percentage were resistant. Finally, a good correlation between the two methods was observed.

UI MeSH Term Description Entries
D008826 Microbial Sensitivity Tests Any tests that demonstrate the relative efficacy of different chemotherapeutic agents against specific microorganisms (i.e., bacteria, fungi, viruses). Bacterial Sensitivity Tests,Drug Sensitivity Assay, Microbial,Minimum Inhibitory Concentration,Antibacterial Susceptibility Breakpoint Determination,Antibiogram,Antimicrobial Susceptibility Breakpoint Determination,Bacterial Sensitivity Test,Breakpoint Determination, Antibacterial Susceptibility,Breakpoint Determination, Antimicrobial Susceptibility,Fungal Drug Sensitivity Tests,Fungus Drug Sensitivity Tests,Sensitivity Test, Bacterial,Sensitivity Tests, Bacterial,Test, Bacterial Sensitivity,Tests, Bacterial Sensitivity,Viral Drug Sensitivity Tests,Virus Drug Sensitivity Tests,Antibiograms,Concentration, Minimum Inhibitory,Concentrations, Minimum Inhibitory,Inhibitory Concentration, Minimum,Inhibitory Concentrations, Minimum,Microbial Sensitivity Test,Minimum Inhibitory Concentrations,Sensitivity Test, Microbial,Sensitivity Tests, Microbial,Test, Microbial Sensitivity,Tests, Microbial Sensitivity
D002175 Candida A genus of yeast-like mitosporic Saccharomycetales fungi characterized by producing yeast cells, mycelia, pseudomycelia, and blastophores. It is commonly part of the normal flora of the skin, mouth, intestinal tract, and vagina, but can cause a variety of infections, including CANDIDIASIS; ONYCHOMYCOSIS; VULVOVAGINAL CANDIDIASIS; and CANDIDIASIS, ORAL (THRUSH). Candida guilliermondii var. nitratophila,Candida utilis,Cyberlindnera jadinii,Hansenula jadinii,Lindnera jadinii,Monilia,Pichia jadinii,Saccharomyces jadinii,Torula utilis,Torulopsis utilis,Monilias
D003470 Culture Media Any liquid or solid preparation made specifically for the growth, storage, or transport of microorganisms or other types of cells. The variety of media that exist allow for the culturing of specific microorganisms and cell types, such as differential media, selective media, test media, and defined media. Solid media consist of liquid media that have been solidified with an agent such as AGAR or GELATIN. Media, Culture
D004058 Diffusion The tendency of a gas or solute to pass from a point of higher pressure or concentration to a point of lower pressure or concentration and to distribute itself throughout the available space. Diffusion, especially FACILITATED DIFFUSION, is a major mechanism of BIOLOGICAL TRANSPORT. Diffusions
D000362 Agar A complex sulfated polymer of galactose units, extracted from Gelidium cartilagineum, Gracilaria confervoides, and related red algae. It is used as a gel in the preparation of solid culture media for microorganisms, as a bulk laxative, in making emulsions, and as a supporting medium for immunodiffusion and immunoelectrophoresis.
D000935 Antifungal Agents Substances that destroy fungi by suppressing their ability to grow or reproduce. They differ from FUNGICIDES, INDUSTRIAL because they defend against fungi present in human or animal tissues. Anti-Fungal Agents,Antifungal Agent,Fungicides, Therapeutic,Antibiotics, Antifungal,Therapeutic Fungicides,Agent, Antifungal,Anti Fungal Agents,Antifungal Antibiotics

Related Publications

M Trancassini, and M C Ghezzi, and P Cipriani, and C Mancini, and M I Brenciaglia
Correlation of netilmicin disk diffusion susceptibility and agar dilution susceptibility.
June 1979, Antimicrobial agents and chemotherapy,
M Trancassini, and M C Ghezzi, and P Cipriani, and C Mancini, and M I Brenciaglia
Antimicrobial susceptibility of Brazilian Clostridium difficile strains determined by agar dilution and disk diffusion.
January 2016, The Brazilian journal of infectious diseases : an official publication of the Brazilian Society of Infectious Diseases,
M Trancassini, and M C Ghezzi, and P Cipriani, and C Mancini, and M I Brenciaglia
Correlation of moxalactam (LY127935) susceptibility tests by disk diffusion and agar plate dilution methods.
January 1981, Antimicrobial agents and chemotherapy,
M Trancassini, and M C Ghezzi, and P Cipriani, and C Mancini, and M I Brenciaglia
[Imipenem: correlation between agar diffusion tests and agar dilution tests].
January 1987, L'union medicale du Canada,
M Trancassini, and M C Ghezzi, and P Cipriani, and C Mancini, and M I Brenciaglia
Comparing the disk-diffusion and agar dilution tests for Neisseria gonorrhoeae antimicrobial susceptibility testing.
January 2016, Antimicrobial resistance and infection control,
M Trancassini, and M C Ghezzi, and P Cipriani, and C Mancini, and M I Brenciaglia
Agar dilution and disk diffusion susceptibility testing of Campylobacter spp.
August 2007, Journal of clinical microbiology,
M Trancassini, and M C Ghezzi, and P Cipriani, and C Mancini, and M I Brenciaglia
Aztreonam: correlation between disk diffusion and agar plate dilutions susceptibility tests.
January 1985, Chemotherapy,
M Trancassini, and M C Ghezzi, and P Cipriani, and C Mancini, and M I Brenciaglia
Susceptibility of Mycobacterium fortuitum to antibacterial agents as evaluated by disk diffusion and agar dilution methods.
November 1983, Bollettino dell'Istituto sieroterapico milanese,
M Trancassini, and M C Ghezzi, and P Cipriani, and C Mancini, and M I Brenciaglia
Evaluation of interpretive criteria of agar dilution and disk diffusion susceptibility tests for Neisseria gonorrhoeae.
March 1994, Diagnostic microbiology and infectious disease,
M Trancassini, and M C Ghezzi, and P Cipriani, and C Mancini, and M I Brenciaglia
Critical evaluation of amdinocillin disk susceptibility tests correlated with agar dilution tests.
May 1986, Journal of clinical microbiology,
Copied contents to your clipboard!